Bioconversion of fumaric acid to succinic acid by recombinant E. coli

Succinic acid was produced efficiently from fumaric acid by a recombinant E. coli strain DH5alpha/pGC1002 containing multicopy fumarate reductase genes. The effects of initial fumaric acid and glucose concentration on the production of succinic acid were investigated. Succinic acid reached 41 to ove...

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Veröffentlicht in:	Applied biochemistry and biotechnology 1998, Vol.70, p.919-928
Hauptverfasser:	Wang, X. (Purdue University, West Lafayette, IN.), Gong, C.S, Tsao, G.T
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetic Acid - chemistry ACIDE FUMARIQUE ACIDE SUCCINIQUE ACIDO FUMARICO ACIDO SUCCINICO BIOCONVERSION Bioconversions. Hemisynthesis Biological and medical sciences Biotechnology ESCHERICHIA COLI Escherichia coli - genetics Escherichia coli - metabolism Fermentation Fumarates - metabolism FUMARIC ACID Fundamental and applied biological sciences. Psychology Glucose - chemistry Malates - chemistry Methods. Procedures. Technologies Succinate Dehydrogenase - genetics SUCCINIC ACID Succinic Acid - metabolism
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