Long-term expression of human clotting factor IX from retrovirally transduced primary human keratinocytes in vivo

A persistent obstacle that has hampered gene transfer experiments is the short-term nature of transgene expression in vivo. In this article we present evidence for sustained expression from primary human keratinocytes, using the retroviral vector MFG. Primary keratinocytes were transduced in culture...

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Veröffentlicht in:	Human gene therapy 1998-05, Vol.9 (8), p.1187-1195
Hauptverfasser:	White, S J, Page, S M, Margaritis, P, Brownlee, G G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Factor IX - biosynthesis Gene Transfer Techniques Genetic Vectors Humans Keratinocytes - metabolism Keratinocytes - transplantation Mice Mice, Nude Moloney murine leukemia virus - genetics Time Factors Transduction, Genetic
Online-Zugang:	Volltext
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