Experimental African HEV infection in cynomolgus macaques (Macaca fascicularis)

Experimental infection with hepatitis E virus (HEV) from Africa has not been investigated. Our purpose was to study hepatitis E produced by HEV from Chad (North Africa) and to analyze the genetic sequence of the HEV obtained after animal passage. An HEV‐containing fecal sample from Chad was intraven...

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Veröffentlicht in:	Journal of medical virology 1998-07, Vol.55 (3), p.197-202
Hauptverfasser:	van Cuyck-Gandré, Hélène, Cockman-Thomas, Rebecca, Caudill, Jeffrey D., Asher, Ludmina S. V., Armstrong, Karyn L., Hauroeder, Barbel, Clements, Norma J., Binn, Leonard N., Longer, Charles F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine Transaminase - blood Amino Acid Sequence Animals Bile - virology Biological and medical sciences Chad cynomolgus macaque Enzyme-Linked Immunosorbent Assay Experimental viral diseases and models Feces - virology Genome, Viral Hepatitis Antibodies - blood hepatitis E Hepatitis E - pathology Hepatitis E - virology Hepatitis E virus - genetics Hepatitis E virus - immunology Hepatitis E virus - isolation & purification Hepatitis E virus - ultrastructure HEV genomic variation Humans Infectious diseases Liver - pathology Macaca fascicularis Male Medical sciences Microscopy, Immunoelectron Molecular Sequence Data Polymerase Chain Reaction Sequence Analysis, DNA Viral diseases Virus Shedding
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