Expression of degradative enzymes and protease inhibitors in corneas with keratoconus

Keratoconus is characterized by thinning and scarring of the central region of the cornea. Previous research showed that, in corneas obtained from patients with keratoconus, lysosomal enzyme activities are elevated, whereas levels of protease inhibitors such as alpha1-proteinase inhibitor are reduce...

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Veröffentlicht in:	Investigative ophthalmology & visual science 1998-06, Vol.39 (7), p.1117-1124
Hauptverfasser:	Zhou, L, Sawaguchi, S, Twining, SS, Sugar, J, Feder, RS, Yue, BY
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Biological and medical sciences Blotting, Western Child Child, Preschool Cornea - enzymology Cornea - pathology Corneal Diseases - enzymology Diseases of cornea, anterior segment and sclera Endopeptidases - metabolism Fluorescent Antibody Technique, Indirect Humans Immunoenzyme Techniques Keratoconus - enzymology Keratoconus - pathology Medical sciences Middle Aged Ophthalmology Protease Inhibitors - metabolism Tissue Plasminogen Activator - metabolism
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