Interaction of growth factors during progression towards steroid independence in T-47-D human breast cancer cells

When deprived of steroid in the long term, T‐47‐D human breast cancer cells lose estrogen sensitivity of cell growth. This loss of response results from an increased basal growth rate in the absence of steroid, not from a loss of estrogen‐simulated growth, and it occurs without any loss of estrogen...

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Veröffentlicht in:Journal of cellular biochemistry 1990-07, Vol.43 (3), p.199-211
Hauptverfasser: Daly, Roger J., King, Roger J. B., Darbre, Philippa D.
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Sprache:eng
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