Polyunsaturated fatty acid regulation of gene expression
For the past three decades, polyunsaturated fatty acids (PUFA) have been recognized as important energy sources and membrane components. PUFA also play key roles in many cellular events, such as gene regulation. Most recently, research has focused on identifying the mechanisms by which PUFA modulate...
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| Veröffentlicht in: | The Journal of nutrition 1998-06, Vol.128 (6), p.923-926 |
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| container_title | The Journal of nutrition |
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| creator | Sessler, A.M. (University of Wisconsin, Madison, WI.) Ntmabi, J.M |
| description | For the past three decades, polyunsaturated fatty acids (PUFA) have been recognized as important energy sources and membrane components. PUFA also play key roles in many cellular events, such as gene regulation. Most recently, research has focused on identifying the mechanisms by which PUFA modulate gene transcription, mRNA stability and cellular differentiation. It is the purpose of this review to examine the effects of PUFA on gene expression in lipogenic as well as other tissues. Because the (n-3) and (n-6) series of PUFA are intimately involved in gene regulation, they will be the focus of review. The effects of other fatty acid families on gene expression are reviewed elsewhere |
| doi_str_mv | 10.1093/jn/128.6.923 |
| format | Article |
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The effects of other fatty acid families on gene expression are reviewed elsewhere</description><identifier>ISSN: 0022-3166</identifier><identifier>EISSN: 1541-6100</identifier><identifier>DOI: 10.1093/jn/128.6.923</identifier><identifier>PMID: 9614148</identifier><identifier>CODEN: JONUAI</identifier><language>eng</language><publisher>Bethesda, MD: American Society for Nutritional Sciences</publisher><subject>ACIDE GRAS POLYINSATURE ; ACIDOS GRASOS POLIINSATURADOS ; Adipocytes - cytology ; Adipose Tissue - cytology ; Adipose Tissue - metabolism ; ADIPOSE TISSUES ; Animals ; Biological and medical sciences ; CELL DIFFERENTIATION ; Cell Differentiation - physiology ; DIFERENCIACION CELULAR ; DIFFERENCIATION CELLULAIRE ; EXPRESION GENICA ; EXPRESSION DES GENES ; Fatty Acids, Unsaturated - physiology ; Feeding. Feeding behavior ; FOIE ; Fundamental and applied biological sciences. Psychology ; GENE EXPRESSION ; Gene Expression Regulation - physiology ; Genes ; HIGADO ; Humans ; IMMUNE SYSTEM ; Immune System - metabolism ; LIPID METABOLISM ; Lipids ; Lipids - biosynthesis ; LIPOGENESE ; LIPOGENESIS ; LITERATURE REVIEWS ; LIVER ; Liver - metabolism ; METABOLISME DES LIPIDES ; METABOLISMO DE LIPIDOS ; MODE OF ACTION ; POLYUNSATURATED FATTY ACIDS ; Proteins ; TEJIDO ADIPOSO ; TISSU ADIPEUX ; Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><ispartof>The Journal of nutrition, 1998-06, Vol.128 (6), p.923-926</ispartof><rights>1998 INIST-CNRS</rights><rights>Copyright American Institute of Nutrition Jun 1998</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c402t-d3c9252de9d9b8a75531bfd03ae8984b33bead7213ad3ed08095ed900cdce93</citedby><cites>FETCH-LOGICAL-c402t-d3c9252de9d9b8a75531bfd03ae8984b33bead7213ad3ed08095ed900cdce93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27906,27907</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2273952$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9614148$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sessler, A.M. (University of Wisconsin, Madison, WI.)</creatorcontrib><creatorcontrib>Ntmabi, J.M</creatorcontrib><title>Polyunsaturated fatty acid regulation of gene expression</title><title>The Journal of nutrition</title><addtitle>J Nutr</addtitle><description>For the past three decades, polyunsaturated fatty acids (PUFA) have been recognized as important energy sources and membrane components. PUFA also play key roles in many cellular events, such as gene regulation. Most recently, research has focused on identifying the mechanisms by which PUFA modulate gene transcription, mRNA stability and cellular differentiation. It is the purpose of this review to examine the effects of PUFA on gene expression in lipogenic as well as other tissues. Because the (n-3) and (n-6) series of PUFA are intimately involved in gene regulation, they will be the focus of review. The effects of other fatty acid families on gene expression are reviewed elsewhere</description><subject>ACIDE GRAS POLYINSATURE</subject><subject>ACIDOS GRASOS POLIINSATURADOS</subject><subject>Adipocytes - cytology</subject><subject>Adipose Tissue - cytology</subject><subject>Adipose Tissue - metabolism</subject><subject>ADIPOSE TISSUES</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>CELL DIFFERENTIATION</subject><subject>Cell Differentiation - physiology</subject><subject>DIFERENCIACION CELULAR</subject><subject>DIFFERENCIATION CELLULAIRE</subject><subject>EXPRESION GENICA</subject><subject>EXPRESSION DES GENES</subject><subject>Fatty Acids, Unsaturated - physiology</subject><subject>Feeding. Feeding behavior</subject><subject>FOIE</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>GENE EXPRESSION</subject><subject>Gene Expression Regulation - physiology</subject><subject>Genes</subject><subject>HIGADO</subject><subject>Humans</subject><subject>IMMUNE SYSTEM</subject><subject>Immune System - metabolism</subject><subject>LIPID METABOLISM</subject><subject>Lipids</subject><subject>Lipids - biosynthesis</subject><subject>LIPOGENESE</subject><subject>LIPOGENESIS</subject><subject>LITERATURE REVIEWS</subject><subject>LIVER</subject><subject>Liver - metabolism</subject><subject>METABOLISME DES LIPIDES</subject><subject>METABOLISMO DE LIPIDOS</subject><subject>MODE OF ACTION</subject><subject>POLYUNSATURATED FATTY ACIDS</subject><subject>Proteins</subject><subject>TEJIDO ADIPOSO</subject><subject>TISSU ADIPEUX</subject><subject>Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><issn>0022-3166</issn><issn>1541-6100</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkEFr3DAQRkVpSTdJb7kGTCk5xRuNJNuaYwhtUgi0kPQsxtJ48eK1t5IN2X9flSwp9DQw3-Ob4QlxAXINEvXNdrwBZdf1GpV-J1ZQGShrkPK9WEmpVKmhrj-K05S2UkowaE_ECdZgwNiVsD-n4bCMieYl0syh6GieDwX5PhSRN8tAcz-NxdQVGx654Jd95JTy6lx86GhI_Ok4z8TTt6_Pdw_l44_773e3j6U3Us1l0B5VpQJjwNZSU1Ua2i5ITWzRmlbrlik0CjQFzUFaiRUHlNIHz6jPxNVr6z5OvxdOs9v1yfMw0MjTklyDCI2tdAY__wdupyWO-TMH2BhjalAZun6FfJxSity5fex3FA8OpPvr0m1Hl1262mWXGb88di7tjsMbfJSX8y_HnJKnoYs0-j69YUo1Giv1r6ajydEmZuTXEyA2-SDUlf4Di3GEYQ</recordid><startdate>19980601</startdate><enddate>19980601</enddate><creator>Sessler, A.M. (University of Wisconsin, Madison, WI.)</creator><creator>Ntmabi, J.M</creator><general>American Society for Nutritional Sciences</general><general>American Institute of Nutrition</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>19980601</creationdate><title>Polyunsaturated fatty acid regulation of gene expression</title><author>Sessler, A.M. (University of Wisconsin, Madison, WI.) ; Ntmabi, J.M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c402t-d3c9252de9d9b8a75531bfd03ae8984b33bead7213ad3ed08095ed900cdce93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>ACIDE GRAS POLYINSATURE</topic><topic>ACIDOS GRASOS POLIINSATURADOS</topic><topic>Adipocytes - cytology</topic><topic>Adipose Tissue - cytology</topic><topic>Adipose Tissue - metabolism</topic><topic>ADIPOSE TISSUES</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>CELL DIFFERENTIATION</topic><topic>Cell Differentiation - physiology</topic><topic>DIFERENCIACION CELULAR</topic><topic>DIFFERENCIATION CELLULAIRE</topic><topic>EXPRESION GENICA</topic><topic>EXPRESSION DES GENES</topic><topic>Fatty Acids, Unsaturated - physiology</topic><topic>Feeding. Feeding behavior</topic><topic>FOIE</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>GENE EXPRESSION</topic><topic>Gene Expression Regulation - physiology</topic><topic>Genes</topic><topic>HIGADO</topic><topic>Humans</topic><topic>IMMUNE SYSTEM</topic><topic>Immune System - metabolism</topic><topic>LIPID METABOLISM</topic><topic>Lipids</topic><topic>Lipids - biosynthesis</topic><topic>LIPOGENESE</topic><topic>LIPOGENESIS</topic><topic>LITERATURE REVIEWS</topic><topic>LIVER</topic><topic>Liver - metabolism</topic><topic>METABOLISME DES LIPIDES</topic><topic>METABOLISMO DE LIPIDOS</topic><topic>MODE OF ACTION</topic><topic>POLYUNSATURATED FATTY ACIDS</topic><topic>Proteins</topic><topic>TEJIDO ADIPOSO</topic><topic>TISSU ADIPEUX</topic><topic>Vertebrates: anatomy and physiology, studies on body, several organs or systems</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sessler, A.M. 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(University of Wisconsin, Madison, WI.)</au><au>Ntmabi, J.M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Polyunsaturated fatty acid regulation of gene expression</atitle><jtitle>The Journal of nutrition</jtitle><addtitle>J Nutr</addtitle><date>1998-06-01</date><risdate>1998</risdate><volume>128</volume><issue>6</issue><spage>923</spage><epage>926</epage><pages>923-926</pages><issn>0022-3166</issn><eissn>1541-6100</eissn><coden>JONUAI</coden><abstract>For the past three decades, polyunsaturated fatty acids (PUFA) have been recognized as important energy sources and membrane components. PUFA also play key roles in many cellular events, such as gene regulation. Most recently, research has focused on identifying the mechanisms by which PUFA modulate gene transcription, mRNA stability and cellular differentiation. It is the purpose of this review to examine the effects of PUFA on gene expression in lipogenic as well as other tissues. 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| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | ACIDE GRAS POLYINSATURE ACIDOS GRASOS POLIINSATURADOS Adipocytes - cytology Adipose Tissue - cytology Adipose Tissue - metabolism ADIPOSE TISSUES Animals Biological and medical sciences CELL DIFFERENTIATION Cell Differentiation - physiology DIFERENCIACION CELULAR DIFFERENCIATION CELLULAIRE EXPRESION GENICA EXPRESSION DES GENES Fatty Acids, Unsaturated - physiology Feeding. Feeding behavior FOIE Fundamental and applied biological sciences. Psychology GENE EXPRESSION Gene Expression Regulation - physiology Genes HIGADO Humans IMMUNE SYSTEM Immune System - metabolism LIPID METABOLISM Lipids Lipids - biosynthesis LIPOGENESE LIPOGENESIS LITERATURE REVIEWS LIVER Liver - metabolism METABOLISME DES LIPIDES METABOLISMO DE LIPIDOS MODE OF ACTION POLYUNSATURATED FATTY ACIDS Proteins TEJIDO ADIPOSO TISSU ADIPEUX Vertebrates: anatomy and physiology, studies on body, several organs or systems |
| title | Polyunsaturated fatty acid regulation of gene expression |
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