Spontaneous Loss of Viral Episomes Accompanying Epstein-Barr Virus Reactivation in a Burkitt's Lymphoma Cell Line

Life-long viral persistence is a hallmark of human herpesvirus infection. In the Epstein-Barr virus (EBV)-positive Burkitt's lymphoma (BL) cell line, Mutu, spontaneous loss of all viral episomes accompanied productive viral DNA replication. The molecular configuration of intracellular EBV DNA e...

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Veröffentlicht in:	The Journal of infectious diseases 1998-06, Vol.177 (6), p.1705-1709
Hauptverfasser:	Srinivas, Shamala K., Sample, Jeffery T., Sixbey, John W.
Format:	Artikel
Sprache:	eng
Schlagworte:	B cell lymphoma Biological and medical sciences Burkitt lymphoma Burkitt Lymphoma - virology Cell lines Concise Communications Delta cells DNA DNA probes DNA, Viral DNA-Binding Proteins - analysis Epstein Barr virus infections Experimental viral diseases and models Fundamental and applied biological sciences. Psychology Herpesvirus 4, Human - genetics Herpesvirus 4, Human - growth & development Herpesvirus 4, Human - metabolism Human herpesvirus 4 Humans Infectious diseases Medical sciences Microbiology Phenotypes Plasmids Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains Trans-Activators - analysis Tumor cell line Tumor Cells, Cultured Viral diseases Viral Proteins Virology Virus Activation Virus Integration
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