Physicochemical determinants in hepatic extraction of small peptides

Although the liver is known to extract amino acids and organic anions by well‐characterized transport systems, the factors that regulate the hepatic uptake of small, circulating peptides are poorly understood. We previously reported that cholecystokinin octapeptide, a biologically active form of cho...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 1990-07, Vol.12 (1), p.76-82
Hauptverfasser:	Hunter, Ellen B., Powers, Stephen P., Kost, Louis J., Pinon, Delia I., Miller, Laurence J., LaRusso, Nicholas F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Bile - metabolism Indicators and Reagents Liver - metabolism Molecular Sequence Data Oligopeptides - chemical synthesis Oligopeptides - metabolism Rats Sincalide - metabolism Structure-Activity Relationship
Online-Zugang:	Volltext
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