The phenylalanyl-tRNA synthetase specifically binds DNA

The phenylalanyl-tRNA synthetase (FRS) from Thermus thermophilus is modularly composed of several different domains, some of which are not required for aminoacylation. In particular, the enzyme has the structural prerequisites for a DNA-binding protein. We demonstrate by gel retardation and competit...

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Veröffentlicht in:	Journal of molecular biology 1998-05, Vol.278 (5), p.897-901
Hauptverfasser:	Lechler, A, Kreutzer, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Acylation Amino Acids - metabolism DNA, Bacterial - metabolism Phenylalanine-tRNA Ligase - metabolism Protein Binding Substrate Specificity Thermus thermophilus
Online-Zugang:	Volltext
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