Glomerular pathology: recent advances
The last decade has seen significant advances in the fields of cellular and molecular biology and pathology. These have contributed to our understanding of the mechanisms of glomerular disease and indicate possible novel approaches to therapy. This review discusses recent insights into the pathogene...
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| Veröffentlicht in: | The Journal of pathology 1998-02, Vol.184 (2), p.123-129 |
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| container_title | The Journal of pathology |
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| creator | Gibson, I. W. More, I. A. R. |
| description | The last decade has seen significant advances in the fields of cellular and molecular biology and pathology. These have contributed to our understanding of the mechanisms of glomerular disease and indicate possible novel approaches to therapy. This review discusses recent insights into the pathogenesis of glomerular disease, with consideration of the roles of intrinsic glomerular cells, infiltrating inflammatory cells, circulating permeability factors, and antibodies, and recent advances in the molecular pathology of the glomerular basement membrane. Changes in the perception of some well‐established glomerular entities such as focal segmental glomerulosclerosis are considered. In addition, a number of newly‐recognized specific glomerulopathies including collapsing glomerulopathy, fibrillary and immunotactoid glomerulopathy, fibronectin glomerulopathy, and collagenofibrotic glomerulopathy are briefly reviewed. © 1998 John Wiley & Sons, Ltd. |
| doi_str_mv | 10.1002/(SICI)1096-9896(199802)184:2<123::AID-PATH16>3.0.CO;2-X |
| format | Article |
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W.</creatorcontrib><creatorcontrib>More, I. A. R.</creatorcontrib><title>Glomerular pathology: recent advances</title><title>The Journal of pathology</title><addtitle>J. Pathol</addtitle><description>The last decade has seen significant advances in the fields of cellular and molecular biology and pathology. These have contributed to our understanding of the mechanisms of glomerular disease and indicate possible novel approaches to therapy. This review discusses recent insights into the pathogenesis of glomerular disease, with consideration of the roles of intrinsic glomerular cells, infiltrating inflammatory cells, circulating permeability factors, and antibodies, and recent advances in the molecular pathology of the glomerular basement membrane. Changes in the perception of some well‐established glomerular entities such as focal segmental glomerulosclerosis are considered. In addition, a number of newly‐recognized specific glomerulopathies including collapsing glomerulopathy, fibrillary and immunotactoid glomerulopathy, fibronectin glomerulopathy, and collagenofibrotic glomerulopathy are briefly reviewed. © 1998 John Wiley & Sons, Ltd.</description><subject>AIDS/HIV</subject><subject>Basement Membrane - metabolism</subject><subject>Biological and medical sciences</subject><subject>glomerular basement membrane</subject><subject>glomerular pathology</subject><subject>Glomerulonephritis</subject><subject>Glomerulonephritis - etiology</subject><subject>glomerulopathy</subject><subject>Glomerulosclerosis, Focal Segmental - etiology</subject><subject>HIV Infections - complications</subject><subject>Humans</subject><subject>Kidney Diseases - etiology</subject><subject>Kidney Glomerulus</subject><subject>Medical sciences</subject><subject>Nephrology. Urinary tract diseases</subject><subject>Nephropathies. Renovascular diseases. Renal failure</subject><subject>Nephrotic Syndrome - etiology</subject><issn>0022-3417</issn><issn>1096-9896</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkF1v0zAUhi0EGqXwE5B6AWi7SPG34zINVQG6ShMdWtHG1ZGTnLBA2hS7BfrvcZWoNyBxY0s-rx-95yHkLaNjRil_fXozz-ZnjFqd2NTqU2ZtSvkZS-WEnzMuJpPp_F1yPV1eMn0hxnScLd7w5O4BGRz_PCSDSOKJkMw8Jk9C-EYptVapE3JiNeWGsgF5OWvaFfpd4_xo47b3bdN-3U9GHgtcb0eu_OnWBYan5FHlmoDP-ntIPn94v8wuk6vFbJ5Nr5JCCqWT1GIpBZM6VZYaJqXgKlfOIuacijQXvEyRVaiVzasy14VJKXUVFYVB5xiKIXnVcTe-_bHDsIVVHQpsGrfGdhfAxL0Yi6whue2ChW9D8FjBxtcr5_fAKBwEAhwEwkEGHGRAJxCiQIgnFwBRIHQCQQCFbBEHd5H8vK-wy1dYHrm9sTh_0c9dKFxT-SioDscYj2guZIx96WK_6gb3f7X7X7l_dutfIjvp2HXY4u8j2_nvoI0wCm4_zkDdmJn-tJRwLf4AlYamnA</recordid><startdate>199802</startdate><enddate>199802</enddate><creator>Gibson, I. W.</creator><creator>More, I. A. 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R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4356-89ed4314685907144325b5a9eeb2038b32d8e1fe659bfdb6c7800af03c7eaa1e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>AIDS/HIV</topic><topic>Basement Membrane - metabolism</topic><topic>Biological and medical sciences</topic><topic>glomerular basement membrane</topic><topic>glomerular pathology</topic><topic>Glomerulonephritis</topic><topic>Glomerulonephritis - etiology</topic><topic>glomerulopathy</topic><topic>Glomerulosclerosis, Focal Segmental - etiology</topic><topic>HIV Infections - complications</topic><topic>Humans</topic><topic>Kidney Diseases - etiology</topic><topic>Kidney Glomerulus</topic><topic>Medical sciences</topic><topic>Nephrology. Urinary tract diseases</topic><topic>Nephropathies. Renovascular diseases. Renal failure</topic><topic>Nephrotic Syndrome - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gibson, I. W.</creatorcontrib><creatorcontrib>More, I. A. R.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gibson, I. W.</au><au>More, I. A. R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Glomerular pathology: recent advances</atitle><jtitle>The Journal of pathology</jtitle><addtitle>J. Pathol</addtitle><date>1998-02</date><risdate>1998</risdate><volume>184</volume><issue>2</issue><spage>123</spage><epage>129</epage><pages>123-129</pages><issn>0022-3417</issn><eissn>1096-9896</eissn><coden>JPTLAS</coden><abstract>The last decade has seen significant advances in the fields of cellular and molecular biology and pathology. These have contributed to our understanding of the mechanisms of glomerular disease and indicate possible novel approaches to therapy. This review discusses recent insights into the pathogenesis of glomerular disease, with consideration of the roles of intrinsic glomerular cells, infiltrating inflammatory cells, circulating permeability factors, and antibodies, and recent advances in the molecular pathology of the glomerular basement membrane. Changes in the perception of some well‐established glomerular entities such as focal segmental glomerulosclerosis are considered. 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| ispartof | The Journal of pathology, 1998-02, Vol.184 (2), p.123-129 |
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| language | eng |
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| source | MEDLINE; Access via Wiley Online Library |
| subjects | AIDS/HIV Basement Membrane - metabolism Biological and medical sciences glomerular basement membrane glomerular pathology Glomerulonephritis Glomerulonephritis - etiology glomerulopathy Glomerulosclerosis, Focal Segmental - etiology HIV Infections - complications Humans Kidney Diseases - etiology Kidney Glomerulus Medical sciences Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Nephrotic Syndrome - etiology |
| title | Glomerular pathology: recent advances |
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