Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not women in the Framingham Heart Study

There is controversy regarding the association of the angiotensin-converting enzyme deletion-insertion (ACE D/I) polymorphism with systemic hypertension and with blood pressure. We investigated these relations in a large population-based sample of men and women by using association and linkage analy...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 1998-05, Vol.97 (18), p.1766-1772
Hauptverfasser:	O'DONNELL, C. J, LINDPAINTNER, K, LARSON, M. G, RAO, V. S, ORDOVAS, J. M, SCHAEFER, E. J, MYERS, R. H, LEVY, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Blood Pressure - genetics Cardiology. Vascular system Cardiovascular Diseases - epidemiology Clinical manifestations. Epidemiology. Investigative techniques. Etiology Cohort Studies Female Genetic Linkage Genotype Human Growth Hormone - genetics Humans Hypertension - epidemiology Hypertension - genetics Hypertension - physiopathology Linear Models Male Medical sciences Microsatellite Repeats Middle Aged Odds Ratio Peptidyl-Dipeptidase A - genetics Polymorphism, Genetic Prospective Studies Quantitative Trait, Heritable Risk Factors Sex Characteristics United States - epidemiology
Online-Zugang:	Volltext
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