Albendazole kinetics in patients with echinococcosis : delayed absorption and impaired elimination in cholestasis

The pharmacokinetics of albendazole and its main metabolite, albendazole sulphoxide, have been examined after giving a single oral dose of 200 mg albendazole to 19 patients with either Echinococcus multilocularis or E. granulosus, 5 of whom had significant extrahepatic obstruction due to the underly...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of clinical pharmacology 1990-01, Vol.38 (6), p.605-608
Hauptverfasser:	COTTING, J, ZEUGIN, T, STEIGER, U, REICHEN, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Albendazole - analogs & derivatives Albendazole - metabolism Albendazole - pharmacokinetics Antibiotics. Antiinfectious agents. Antiparasitic agents Antiparasitic agents Biological and medical sciences Cholestasis - metabolism Echinococcosis - metabolism Female Half-Life Humans Intestinal Absorption Male Medical sciences Middle Aged Pharmacology. Drug treatments
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!