Steroid production by early pregnancy human placental villi in culture

Organ cultures prepared from human placentae obtained at 7–12 weeks of gestation were maintained for 3–13 days in Dulbecco's modified Eagle medium (DMEM). The addition of pregnenolone to the medium resulted in a dose-related increase in progesterone production and the addition of androstenedion...

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Veröffentlicht in:	Placenta (Eastbourne) 1990-05, Vol.11 (3), p.277-288
Hauptverfasser:	Maslar, Ila A., Hess, David L., Buckmaster, John G., Lazur, Jessica J., Stanczyk, Frank Z., Novy, Miles J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Androstenedione - metabolism Chorionic Villi - metabolism Chorionic Villi - ultrastructure Estrogens - biosynthesis Estrone - pharmacology Female Gonadal Steroid Hormones - biosynthesis Humans Organ Culture Techniques Pregnancy Pregnancy Trimester, First - metabolism Pregnenolone - metabolism Progesterone - biosynthesis
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