Investigation of the survival of paroxysmal nocturnal hemoglobinuria red cells through the immunophenotyping of reticulocytes

BACKGROUND: Complement‐mediated lysis of red cells (RBCs) is a classic feature of paroxysmal nocturnal hemoglobinuria (PNH) that is traditionally studied with a combination of radiolabeling of RBCs and in vitro hemolysis tests. Phenotyping of reticulocytes was used as an alternative method for the e...

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Veröffentlicht in:	Transfusion (Philadelphia, Pa.) Pa.), 1998-04, Vol.38 (4), p.337-342
Hauptverfasser:	Navenot, J. M., Muller, J. Y., Blanchard, D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anemias. Hemoglobinopathies Biological and medical sciences CD55 Antigens - blood CD58 Antigens - blood CD59 Antigens - blood Diseases of red blood cells Erythrocyte Aging - physiology Erythrocytes - immunology Female Flow Cytometry Hematologic and hematopoietic diseases Hemoglobinuria, Paroxysmal - blood Hemoglobinuria, Paroxysmal - classification Humans Immunophenotyping Male Medical sciences Reticulocytes - immunology
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