Reversibility of pulmonary artery hypertension in aortic stenosis after aortic valve replacement
Fifty-two surgical patients with isolated aortic valve stenosis were studied preoperatively and postoperatively to determine the incidence of pulmonary hypertension and its response to surgical intervention. Pulmonary artery systolic hypertension was classified as absent (group 1, < 30 mm Hg), mi...
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| Veröffentlicht in: | The Annals of thoracic surgery 1990-07, Vol.50 (1), p.89-93 |
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| creator | Tracy, Gerald P. Proctor, Michael S. Hizny, Cathleen S. |
| description | Fifty-two surgical patients with isolated aortic valve stenosis were studied preoperatively and postoperatively to determine the incidence of pulmonary hypertension and its response to surgical intervention. Pulmonary artery systolic hypertension was classified as absent (group 1, < 30 mm Hg), mild (group 2, 30 to 39 mm Hg), moderate (group 3, 40 to 59 mm Hg), and severe (group 4, >60 mm Hg). Thirty-seven of our patients (71%) had preoperative pulmonary hypertension. There was a positive correlation between left ventricular end-diastolic pressure and both systolic and diastolic pulmonary artery pressures preoperatively (p |
| doi_str_mv | 10.1016/0003-4975(90)90095-N |
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Pulmonary artery systolic hypertension was classified as absent (group 1, < 30 mm Hg), mild (group 2, 30 to 39 mm Hg), moderate (group 3, 40 to 59 mm Hg), and severe (group 4, >60 mm Hg). Thirty-seven of our patients (71%) had preoperative pulmonary hypertension. There was a positive correlation between left ventricular end-diastolic pressure and both systolic and diastolic pulmonary artery pressures preoperatively (p<0.001). After operation we found a decrease in mean systolic pulmonary pressure in group 4, from 85.8 ± 23 mm Hg to 41.2 ± 10.4 mm Hg (a 52% decrease, p < 0.001), and in group 3, from 48.9 ± 5.9 mm Hg to 32.1 ± 7.1 mm Hg (a 34% decrease, p < 0.001). A significant decrease in the mean diastolic pressure was found only in group 4, in which the pressure decreased from 33.7 ± 8.7 mm Hg to 26.0 ± 7.6 mm Hg (p < 0.05). The operative mortality was 1.9%. Our data indicate that pulmonary artery hypertension in aortic stenosis is common, is related to end-diastolic pressure, and can be expected to improve in the early postoperative period.</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/0003-4975(90)90095-N</identifier><identifier>PMID: 2369233</identifier><identifier>CODEN: ATHSAK</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Aged ; Aortic Valve - physiopathology ; Aortic Valve - surgery ; Aortic Valve Stenosis - physiopathology ; Aortic Valve Stenosis - surgery ; Biological and medical sciences ; Blood Pressure - physiology ; Cardiology. Vascular system ; Diastole ; Endocardial and cardiac valvular diseases ; Female ; Heart ; Heart Valve Prosthesis ; Humans ; Hypertension, Pulmonary - physiopathology ; Hypertension, Pulmonary - therapy ; Male ; Medical sciences ; Middle Aged ; Pulmonary Artery - physiopathology ; Retrospective Studies ; Vascular Resistance</subject><ispartof>The Annals of thoracic surgery, 1990-07, Vol.50 (1), p.89-93</ispartof><rights>1990 The Society of Thoracic Surgeons</rights><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c538t-7690d590f060c33b23c345701bdb80c98dd2108a151f9d4384f67ff97ddf48833</citedby><cites>FETCH-LOGICAL-c538t-7690d590f060c33b23c345701bdb80c98dd2108a151f9d4384f67ff97ddf48833</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19360609$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2369233$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tracy, Gerald P.</creatorcontrib><creatorcontrib>Proctor, Michael S.</creatorcontrib><creatorcontrib>Hizny, Cathleen S.</creatorcontrib><title>Reversibility of pulmonary artery hypertension in aortic stenosis after aortic valve replacement</title><title>The Annals of thoracic surgery</title><addtitle>Ann Thorac Surg</addtitle><description>Fifty-two surgical patients with isolated aortic valve stenosis were studied preoperatively and postoperatively to determine the incidence of pulmonary hypertension and its response to surgical intervention. Pulmonary artery systolic hypertension was classified as absent (group 1, < 30 mm Hg), mild (group 2, 30 to 39 mm Hg), moderate (group 3, 40 to 59 mm Hg), and severe (group 4, >60 mm Hg). Thirty-seven of our patients (71%) had preoperative pulmonary hypertension. There was a positive correlation between left ventricular end-diastolic pressure and both systolic and diastolic pulmonary artery pressures preoperatively (p<0.001). After operation we found a decrease in mean systolic pulmonary pressure in group 4, from 85.8 ± 23 mm Hg to 41.2 ± 10.4 mm Hg (a 52% decrease, p < 0.001), and in group 3, from 48.9 ± 5.9 mm Hg to 32.1 ± 7.1 mm Hg (a 34% decrease, p < 0.001). A significant decrease in the mean diastolic pressure was found only in group 4, in which the pressure decreased from 33.7 ± 8.7 mm Hg to 26.0 ± 7.6 mm Hg (p < 0.05). The operative mortality was 1.9%. Our data indicate that pulmonary artery hypertension in aortic stenosis is common, is related to end-diastolic pressure, and can be expected to improve in the early postoperative period.</description><subject>Aged</subject><subject>Aortic Valve - physiopathology</subject><subject>Aortic Valve - surgery</subject><subject>Aortic Valve Stenosis - physiopathology</subject><subject>Aortic Valve Stenosis - surgery</subject><subject>Biological and medical sciences</subject><subject>Blood Pressure - physiology</subject><subject>Cardiology. Vascular system</subject><subject>Diastole</subject><subject>Endocardial and cardiac valvular diseases</subject><subject>Female</subject><subject>Heart</subject><subject>Heart Valve Prosthesis</subject><subject>Humans</subject><subject>Hypertension, Pulmonary - physiopathology</subject><subject>Hypertension, Pulmonary - therapy</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pulmonary Artery - physiopathology</subject><subject>Retrospective Studies</subject><subject>Vascular Resistance</subject><issn>0003-4975</issn><issn>1552-6259</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtO5DAQRS00iGkefwBSNjOCRaAcx0m8QRohXhICCcHaOHZZeJTEwU631H-Pm25gx6rsureuXYeQQwqnFGh1BgAsL0XNjwWcCADB8_stMqOcF3lVcPGLzL4sv8lujP_TtUjyDtkpWCUKxmbk5REXGKJrXeemZeZtNs673g8qLDMVJkzldTliOg3R-SFzQ6Z8mJzOYmr56GKmbLJ9dheqW2AWcOyUxh6HaZ9sW9VFPNjUPfJ8dfl0cZPfPVzfXvy7yzVnzZTXlQDDBVioQDPWFkyzktdAW9M2oEVjTEGhUZRTK0zJmtJWtbWiNsaWTcPYHvm7zh2Df5tjnGTvosauUwP6eZS1aOq6KkQylmujDj7GgFaOwfVpX0lBrsDKFTW5oiYFyA-w8j6NHW3y522P5mtoQzLpfza6ilp1NqhBu_idLViVVls9f772YYKxcBhk1A4HjcYF1JM03v38kXcqNpXh</recordid><startdate>19900701</startdate><enddate>19900701</enddate><creator>Tracy, Gerald P.</creator><creator>Proctor, Michael S.</creator><creator>Hizny, Cathleen S.</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19900701</creationdate><title>Reversibility of pulmonary artery hypertension in aortic stenosis after aortic valve replacement</title><author>Tracy, Gerald P. ; Proctor, Michael S. ; Hizny, Cathleen S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c538t-7690d590f060c33b23c345701bdb80c98dd2108a151f9d4384f67ff97ddf48833</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Aged</topic><topic>Aortic Valve - physiopathology</topic><topic>Aortic Valve - surgery</topic><topic>Aortic Valve Stenosis - physiopathology</topic><topic>Aortic Valve Stenosis - surgery</topic><topic>Biological and medical sciences</topic><topic>Blood Pressure - physiology</topic><topic>Cardiology. Vascular system</topic><topic>Diastole</topic><topic>Endocardial and cardiac valvular diseases</topic><topic>Female</topic><topic>Heart</topic><topic>Heart Valve Prosthesis</topic><topic>Humans</topic><topic>Hypertension, Pulmonary - physiopathology</topic><topic>Hypertension, Pulmonary - therapy</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pulmonary Artery - physiopathology</topic><topic>Retrospective Studies</topic><topic>Vascular Resistance</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tracy, Gerald P.</creatorcontrib><creatorcontrib>Proctor, Michael S.</creatorcontrib><creatorcontrib>Hizny, Cathleen S.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tracy, Gerald P.</au><au>Proctor, Michael S.</au><au>Hizny, Cathleen S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Reversibility of pulmonary artery hypertension in aortic stenosis after aortic valve replacement</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>1990-07-01</date><risdate>1990</risdate><volume>50</volume><issue>1</issue><spage>89</spage><epage>93</epage><pages>89-93</pages><issn>0003-4975</issn><eissn>1552-6259</eissn><coden>ATHSAK</coden><abstract>Fifty-two surgical patients with isolated aortic valve stenosis were studied preoperatively and postoperatively to determine the incidence of pulmonary hypertension and its response to surgical intervention. Pulmonary artery systolic hypertension was classified as absent (group 1, < 30 mm Hg), mild (group 2, 30 to 39 mm Hg), moderate (group 3, 40 to 59 mm Hg), and severe (group 4, >60 mm Hg). Thirty-seven of our patients (71%) had preoperative pulmonary hypertension. There was a positive correlation between left ventricular end-diastolic pressure and both systolic and diastolic pulmonary artery pressures preoperatively (p<0.001). After operation we found a decrease in mean systolic pulmonary pressure in group 4, from 85.8 ± 23 mm Hg to 41.2 ± 10.4 mm Hg (a 52% decrease, p < 0.001), and in group 3, from 48.9 ± 5.9 mm Hg to 32.1 ± 7.1 mm Hg (a 34% decrease, p < 0.001). A significant decrease in the mean diastolic pressure was found only in group 4, in which the pressure decreased from 33.7 ± 8.7 mm Hg to 26.0 ± 7.6 mm Hg (p < 0.05). The operative mortality was 1.9%. Our data indicate that pulmonary artery hypertension in aortic stenosis is common, is related to end-diastolic pressure, and can be expected to improve in the early postoperative period.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>2369233</pmid><doi>10.1016/0003-4975(90)90095-N</doi><tpages>5</tpages></addata></record> |
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| subjects | Aged Aortic Valve - physiopathology Aortic Valve - surgery Aortic Valve Stenosis - physiopathology Aortic Valve Stenosis - surgery Biological and medical sciences Blood Pressure - physiology Cardiology. Vascular system Diastole Endocardial and cardiac valvular diseases Female Heart Heart Valve Prosthesis Humans Hypertension, Pulmonary - physiopathology Hypertension, Pulmonary - therapy Male Medical sciences Middle Aged Pulmonary Artery - physiopathology Retrospective Studies Vascular Resistance |
| title | Reversibility of pulmonary artery hypertension in aortic stenosis after aortic valve replacement |
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