Differential expression of c-fos mRNA and Fos protein in the rat brain after restraint stress or pentylenetetrazol-induced seizures

1. c-fos mRNA expression and Fos protein expression were investigated by in situ hybridization and immunohistochemistry after 30 min of forced restraint stress or pentylenetetrazol (PTZ; 64 mg/kg, i.p.)-induced seizures. 2. Forced restraint stress and PTZ-induced seizures generated c-fos mRNA expres...

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Veröffentlicht in:	Cellular and molecular neurobiology 1998-06, Vol.18 (3), p.339-346
Hauptverfasser:	Del Bel, E A, Silveira, M C, Graeff, F G, Garcia-Cairasco, N, Guimarães, F S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - metabolism Brain - physiopathology Gene Expression Regulation - drug effects Genes, fos - drug effects Immobilization Immunohistochemistry In Situ Hybridization Male Oncogene Proteins v-fos - biosynthesis Oncogene Proteins v-fos - genetics Pentylenetetrazole - pharmacology Rats Rats, Wistar RNA, Messenger - biosynthesis RNA, Messenger - drug effects Seizures - chemically induced Seizures - genetics Seizures - metabolism Stress, Physiological - genetics Stress, Physiological - metabolism Stress, Physiological - physiopathology
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