Effects of anoxic stress on prostaglandin H synthase isoforms in piglet brain

We examined effects of ischemia and asphyxia on levels of prostaglandin H synthase-1 (PGHS-1) and prostaglandin H synthase-2 (PGHS-2) in piglet brain. Ischemia was induced by increasing intracranial pressure and asphyxia was induced by turning off the respirator. Duration of anoxic stress was 10 min...

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Veröffentlicht in:	Brain research. Developmental brain research 1998-05, Vol.107 (2), p.265-276
Hauptverfasser:	Dégı̀, Rózsa, Bari, Ferenc, Thrikawala, Nishadi, Beasley, Tracy C, Thore, Clara, Louis, Thomas M, Busija, David W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Asphyxia Body Temperature Brain - enzymology Cerebellum Cerebral cortex Cerebral Cortex - drug effects Cerebral Cortex - enzymology Cyclooxygenase Cyclooxygenase Inhibitors - pharmacology Enzyme Inhibitors - pharmacology Female Hippocampus Hippocampus - drug effects Hippocampus - enzymology Hypoxia, Brain - enzymology Immunohistochemistry Indazoles - pharmacology Indomethacin Indomethacin - pharmacology Ischemia Isoenzymes - biosynthesis Male Nitric oxide synthase Nitric Oxide Synthase - antagonists & inhibitors Prostaglandin H synthase-1 Prostaglandin H synthase-2 Prostaglandin-Endoperoxide Synthases - biosynthesis Ribonucleases - metabolism Swine
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