Myelodysplastic syndromes presenting in pregnancy: A report of five cases and the clinical outcome

Five female patients, ranging in age between 22 and 36 years, presented with myelodysplastic syndromes during pregnancy between June 1982 and March 1987. Three of these five cases evolved into acute leukemia. A bone marrow transplant was attempted in the fourth. It is suggested that the association...

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Veröffentlicht in:Cancer 1990-07, Vol.66 (2), p.377-381
Hauptverfasser: Siddiqui, Tariq, Elfenbein, Gerald J., Noyes, Ward D., Moreb, Jan S., Oblon, David, Weiner, Roy S.
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container_end_page 381
container_issue 2
container_start_page 377
container_title Cancer
container_volume 66
creator Siddiqui, Tariq
Elfenbein, Gerald J.
Noyes, Ward D.
Moreb, Jan S.
Oblon, David
Weiner, Roy S.
description Five female patients, ranging in age between 22 and 36 years, presented with myelodysplastic syndromes during pregnancy between June 1982 and March 1987. Three of these five cases evolved into acute leukemia. A bone marrow transplant was attempted in the fourth. It is suggested that the association of myelodysplastic syndromes during pregnancy is more than coincidental and that acute leukemia evolves in a majority of these cases. Furthermore, refractory macrocytic anemias in pregnancy need to be carefully evaluated for a primary myelodysplastic state.
doi_str_mv 10.1002/1097-0142(19900715)66:2<377::AID-CNCR2820660230>3.0.CO;2-Q
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subjects Adult
Biological and medical sciences
Female
Gynecology. Andrology. Obstetrics
Humans
Leukemia - etiology
Management. Prenatal diagnosis
Medical sciences
Myelodysplastic Syndromes - complications
Pregnancy
Pregnancy Complications, Hematologic - pathology
Pregnancy. Fetus. Placenta
Prognosis
title Myelodysplastic syndromes presenting in pregnancy: A report of five cases and the clinical outcome
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