Dose optimization of intravenous magnesium sulfate after acute stroke

Parenterally administered MgSO4 is neuroprotective in standard animal models of focal cerebral ischemia and in many other paradigms of brain injury. Previous small clinical trials in stroke patients have explored the safety and tolerability of different infusion regimens. This study was undertaken t...

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Veröffentlicht in:	Stroke (1970) 1998-05, Vol.29 (5), p.918-923
Hauptverfasser:	MUIR, K. W, LEES, K. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Aged Anticonvulsants - administration & dosage Anticonvulsants - therapeutic use Biological and medical sciences Blood Glucose - drug effects Blood Glucose - metabolism Blood Pressure - drug effects Blood Pressure - physiology Cerebral Hemorrhage - drug therapy Cerebral Infarction - drug therapy Cerebrovascular Disorders - blood Cerebrovascular Disorders - drug therapy Diastole Double-Blind Method Female Heart Rate - drug effects Heart Rate - physiology Humans Hypotension - etiology Injections, Intravenous Magnesium - blood Magnesium Sulfate - administration & dosage Magnesium Sulfate - therapeutic use Male Medical sciences Neuropharmacology Neuroprotective agent Pharmacology. Drug treatments Systole Time Factors Treatment Outcome
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