Analysis of loss of heterozygosity in 399 premalignant breast lesions at 15 genetic loci

Usual ductal hyperplasia (UDH), atypical ductal hyperplasia (ADH), and ductal carcinoma in situ (DCIS) are risk factors for invasive breast cancer (IBC), suggesting that these lesions may be direct precursors of IBC. To identify genetic changes that may be important in the early development of precu...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 1998-05, Vol.90 (9), p.697-703
Hauptverfasser:	O'CONNELL, P, PEKKEL, V, FUQUA, S. A. W, OSBORNE, C. K, CLARK, G. M, ALLRED, D. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Breast cancer Breast Diseases - genetics Breast Diseases - pathology Breast Neoplasms - genetics Breast Neoplasms - pathology Cell Transformation, Neoplastic Chromosome Deletion Disease Progression DNA Primers DNA, Neoplasm - chemistry Female Genetics Gynecology. Andrology. Obstetrics Heterozygote Humans Hyperplasia Mammary gland diseases Medical sciences Neoplasm Invasiveness Neoplasms, Multiple Primary - genetics Neoplasms, Multiple Primary - pathology Polymerase Chain Reaction Tumors
Online-Zugang:	Volltext
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