Evidence that the Head of Kinesin is Sufficient for Force Generation and Motility in Vitro

Kinesin is a mechanochemical protein that converts the chemical energy in adenosine triphosphate into mechanical force for movement of cellular components along microtubules. The regions of the kinesin molecule responsible for generating movement were determined by studying the heavy chain of Drosop...

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Veröffentlicht in:	Science (American Association for the Advancement of Science) 1990-07, Vol.249 (4964), p.42-47
Hauptverfasser:	Yang, Joy T., Saxton, William M., Stewart, Russell J., Raff, Elizabeth C., Lawrence S. B. Goldstein
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - biosynthesis Adenosine Triphosphatases - genetics Adenosine Triphosphatases - physiology Amino Acid Sequence Amino acids Animals Base Sequence Biochemistry Biological and medical sciences Cell extracts Cell physiology Cells, Cultured Complementary DNA Diptera Drosophila Drosophilidae Escherichia coli Escherichia coli - genetics Escherichia coli - metabolism Fundamental and applied biological sciences. Psychology Innovations Kinesin Male Microtubule Proteins - biosynthesis Microtubule Proteins - genetics Microtubule Proteins - physiology Microtubules Microtubules - physiology Molecular and cellular biology Molecular chains Molecular Sequence Data Molecules Motility and taxis Movement Peptide Fragments - biosynthesis Peptide Fragments - genetics Peptide Fragments - physiology Physiological aspects Plasmids Protein research Proteins Quaternary ammonium compounds Recombinant Proteins - biosynthesis Recombinant Proteins - genetics Recombinant Proteins - physiology Research Article Sea Urchins Spermatozoa Spermatozoa - physiology
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