Sensitization of the Mesoaccumbens Dopamine Response to Nicotine

This article reviews the evidence that pretreatment with nicotine causes a regionally selective sensitization of its stimulatory effects on a pathway, the mesoaccumbens dopamine (DA) system, which has been implicated in the locomotor stimulant response to nicotine and its ability to reinforce self-a...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 1998-04, Vol.59 (4), p.1021-1030
Hauptverfasser:	Balfour, David J.K, Benwell, Maureen E.M, Birrell, Claire E, Kelly, J, Al-Aloul, Mohamed
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Dependence Dopamine - metabolism Dopamine Uptake Inhibitors - pharmacology Dorsolateral striatum Humans Locomotor activity Nicotine - pharmacology Nicotine<Dopamine Nicotinic Agonists - pharmacology NMDA Nomifensine - pharmacology Nucleus accumbens Nucleus Accumbens - drug effects Nucleus Accumbens - metabolism Raclopride Receptors
Online-Zugang:	Volltext
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