Calcipotriol (MC 903), a novel vitamin D3 analogue stimulates terminal differentiation and inhibits proliferation of cultured human keratinocytes

The hormonally active form of vitamin D3, 1,25-dihydroxy vitamin D3 [1,25-(OH)2-D3; calcitriol], regulates the differentiation and proliferation of epidermal keratinocytes in vitro. MC 903 (calcipotriol) is a novel vitamin D3 analogue which is at least 100 times less potent than 1,25-(OH)-2-D3 in it...

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Veröffentlicht in:	Archives of Dermatological Research 1990-01, Vol.282 (3), p.164-167
Hauptverfasser:	KRAGBALLE, K, WILDFANG, I. L
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Calcitriol - analogs & derivatives Calcitriol - pharmacology Cell Differentiation Cell Division - drug effects Cells, Cultured Cholecalciferol - pharmacology General and cellular metabolism. Vitamins Humans Keratinocytes - cytology Keratinocytes - drug effects Medical sciences Pharmacology. Drug treatments
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