Effect of high dose norepinephrine versus epinephrine on cerebral and myocardial blood flow during CPR

Several animal studies have demonstrated an improvement in cerebral blood flow (CBF) and myocardial blood flow (MBF) after the administration of epinephrine (E) 0.20 mg/kg during closed chest CPR. The administration of norepinephrine (NE) in doses of 0.12 and 0.16 mg/kg demonstrated a trend toward i...

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Veröffentlicht in:	Resuscitation 1990-06, Vol.19 (3), p.227-240
Hauptverfasser:	Hoekstra, James W., Van Ligten, Peter, Neumar, Robert, Werman, Howard A., Brown, Judith AndersonCharles G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cardiopulmonary resuscitation Catecholaminergic system Catecholamines Cerebrovascular Circulation - drug effects Coronary Circulation - drug effects Drug Administration Schedule Epinephrine Epinephrine - pharmacology Hemodynamics - drug effects Medical sciences Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Norepinephrine Norepinephrine - pharmacology Pharmacology. Drug treatments Regional blood flow Resuscitation - methods Swine Ventricular fibrillation
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