Adoptive immunotherapy of a rat glioma using lymphokine-activated killer cells and interleukin 2

The aim of the present study was to develop an animal model to test the therapeutic potential of purified adherent lymphokine-activated killer (A-LAK) cells against an intracerebrally implanted rat glioma, designated F98. Highly purified A-LAK cells demonstrated greater activity against F98 tumor ce...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1990-07, Vol.50 (14), p.4338-4343
Hauptverfasser:	JONE-JIUN TZENG, BARTH, R. F, CLENDENON, N. R, GORDON, W. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Biological and medical sciences Brain Neoplasms - immunology Brain Neoplasms - therapy Cytotoxicity, Immunologic Glioma - immunology Glioma - therapy Immunization, Passive Immunotherapy Interleukin-2 - therapeutic use Killer Cells, Lymphokine-Activated - cytology Killer Cells, Lymphokine-Activated - immunology Kinetics Lymphocyte Activation Male Medical sciences Neutralization Tests Pharmacology. Drug treatments Rats Rats, Inbred F344 Tumor Stem Cell Assay
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