Increase in Cyclic AMP Levels by Relaxin in Newborn Rhesus Monkey Uterus Cell Culture

A novel relaxin sensitive cell line of apparent smooth muscle origin has been established from a newborn rhesus monkey uterus (NRMU). NRMU cells respond to relaxin, in the presence of 1 μ M forskolin, by producing intracellular adenosine 3', 5'-cyclic monophosphate (cAMP). The increase in...

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Veröffentlicht in:	In Vitro Cellular & Developmental Biology 1990-06, Vol.26 (6), p.647-656
Hauptverfasser:	Susan Mukavitz Kramer, Ursula E. M. Gibson, Fendly, Brian M., Marjorie A. Mohler, Drolet, Daniel W., Johnston, Paul D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - analysis Alprostadil - pharmacology Animals Animals, Newborn Antibodies Antibodies, Monoclonal Biological and medical sciences Cell culture techniques Cell Line Cell lines Cell physiology Cells, Cultured Colforsin - pharmacology Cultured cells Cyclic AMP - metabolism Epithelial cells Female Fundamental and applied biological sciences. Psychology Hormones Insulin Insulin - pharmacology Insulin-Like Growth Factor I - pharmacology Insulin-Like Growth Factor II - pharmacology Macaca mulatta Molecular and cellular biology Rapid Communications in Cell Biology Recombinant Proteins - pharmacology Relaxin - pharmacology Responses to growth factors, tumor promotors, other factors Smooth muscle Smooth muscle myocytes Uterus Uterus - drug effects Uterus - metabolism
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