Reverse tolerance to amphetamine evokes reverse tolerance to 5-hydroxytryptophan

Repeated intermittent administration of amphetamine in mice caused reverse tolerance to 5-hydroxy- L-tryptophan (5-HTP)-induced head twitch, as well as to amphetamine-induced stereotypy. The repeated administration of 5-HTP alone also resulted in reverse tolerance in the head-twitch test. Daily pret...

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Veröffentlicht in:	Life sciences (1973) 1990, Vol.46 (24), p.1773-1780
Hauptverfasser:	Karler, R., Calder, L.D., Turkanis, S.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	5-Hydroxytryptophan - pharmacology Amphetamine - pharmacology Animals Chi-Square Distribution Cyproheptadine - pharmacology Dose-Response Relationship, Drug Drug Tolerance Haloperidol - pharmacology Male Mice Motor Activity - drug effects Random Allocation Stereotyped Behavior - drug effects
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