Excitation-contraction coupling in heart cells : roles of the sodium-calcium exchange, the calcium current, and the sarcoplasmic reticulum
Experimental data do not support the idea that excitation-contraction coupling in heart muscle can be explained by a simple calcium-induced calcium release mechanism alone or a simple voltage-dependent calcium release mechanism alone. Our data on excitation-contraction coupling combined with the res...
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Veröffentlicht in: | Annals of the New York Academy of Sciences 1990-01, Vol.588 (1), p.190-206 |
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container_title | Annals of the New York Academy of Sciences |
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creator | LEDERER, W. J BERLIN, J. R COHEN, N. M HADLEY, R. W BERS, D. M CANNELL, M. B |
description | Experimental data do not support the idea that excitation-contraction coupling in heart muscle can be explained by a simple calcium-induced calcium release mechanism alone or a simple voltage-dependent calcium release mechanism alone. Our data on excitation-contraction coupling combined with the results of others suggest the need to either develop more complex and more sophisticated single-mechanism models, or to establish dual-control models. |
doi_str_mv | 10.1111/j.1749-6632.1990.tb13210.x |
format | Article |
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Psychology ; Guinea Pigs ; Humans ; Membrane Potentials ; Microscopy, Fluorescence ; Molecular and cellular biology ; Muscle contraction ; Myocardial Contraction ; Myocardium - metabolism ; Myocardium - ultrastructure ; Rats ; Sarcoplasmic Reticulum - metabolism ; Sarcoplasmic Reticulum - physiology ; Sarcoplasmic Reticulum - ultrastructure ; Sodium - metabolism ; Ventricular Function</subject><ispartof>Annals of the New York Academy of Sciences, 1990-01, Vol.588 (1), p.190-206</ispartof><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c287t-9d0a330530ccd5d8ac1d6c2d9250093366aea73321a907464abe4920fca382c33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>309,310,314,780,784,789,790,23928,23929,25138,27922,27923</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19697793$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2357018$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LEDERER, W. 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Our data on excitation-contraction coupling combined with the results of others suggest the need to either develop more complex and more sophisticated single-mechanism models, or to establish dual-control models.</abstract><cop>Malden, MS</cop><pub>Blackwell</pub><pmid>2357018</pmid><doi>10.1111/j.1749-6632.1990.tb13210.x</doi><tpages>17</tpages></addata></record> |
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source | Wiley Online Library - AutoHoldings Journals; MEDLINE |
subjects | Animals Biological and medical sciences Calcium - metabolism Cell physiology Fundamental and applied biological sciences. Psychology Guinea Pigs Humans Membrane Potentials Microscopy, Fluorescence Molecular and cellular biology Muscle contraction Myocardial Contraction Myocardium - metabolism Myocardium - ultrastructure Rats Sarcoplasmic Reticulum - metabolism Sarcoplasmic Reticulum - physiology Sarcoplasmic Reticulum - ultrastructure Sodium - metabolism Ventricular Function |
title | Excitation-contraction coupling in heart cells : roles of the sodium-calcium exchange, the calcium current, and the sarcoplasmic reticulum |
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