Sequential appearance of host-derived T cell subsets during differentiation in nude mice grafted with rat fetal thymus

To elucidate the abnormality of T cell differentiation in nude mice grafted with rat fetal thymus that develop multiple-organ-localized autoimmune diseases, we examined sequential appearance of T cell subsets and expression of TCR genes in BALB/c nude mice after grafting with fetal F344 rat thymus....

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Veröffentlicht in:	The Journal of immunology (1950) 1990-07, Vol.145 (1), p.28-35
Hauptverfasser:	Iwasaki, A, Yoshikai, Y, Sakumoto, M, Himeno, K, Yuuki, H, Kumamoto, M, Sueishi, K, Nomoto, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Antinuclear - immunology Antigens, Differentiation, T-Lymphocyte - analysis Autoimmune Diseases - immunology Biological and medical sciences Blotting, Northern Cell Differentiation Flow Cytometry Fundamental and applied biological sciences. Psychology Fundamental immunology Gene Expression Immunity, Cellular Lymph Nodes - physiology Lymphocyte Culture Test, Mixed Mice Mice, Nude Rats Receptors, Antigen, T-Cell - genetics RNA, Messenger - genetics T-Lymphocytes - cytology T-Lymphocytes - transplantation T-Lymphocytes, Cytotoxic - immunology Thymus Gland - transplantation Tissue, organ and graft immunology
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