Purine biosynthesis in Escherichia coli K12: structure and DNA sequence studies of the purHD locus

Summary The de novo purine biosynthetic enzymes 5‐amino‐4‐imidazolecarboxamide‐ribonucleotide (AICAR) transformylase (EC 2.1.2.3), IMP cyclohydrolase (EC 3.5.4.10) and glycineamide‐ribonucleotide (GAR) synthetase (EC 2.1.2.2) are encoded by the purHD locus of Escherichia coli. The DNA sequence of th...

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Veröffentlicht in:	Molecular microbiology 1990-03, Vol.4 (3), p.381-392
Hauptverfasser:	Flannigan, K. A., Hennigan, S. H., Vogelbacker, H. H., Gots, J. S., Smith, J. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acyltransferases - biosynthesis Acyltransferases - genetics Amino Acid Sequence Bacteriology Base Sequence Biological and medical sciences Carbon-Nitrogen Ligases Cloning, Molecular DNA, Bacterial - analysis Escherichia coli - enzymology Escherichia coli - genetics Fundamental and applied biological sciences. Psychology Genetics Humans Hydroxymethyl and Formyl Transferases Ligases - genetics loci Microbiology Molecular Sequence Data Nucleic Acid Conformation Nucleotide Deaminases - biosynthesis Nucleotide Deaminases - genetics Phosphoribosylaminoimidazolecarboxamide Formyltransferase purines Restriction Mapping Salmonella typhimurium - enzymology Salmonella typhimurium - genetics
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