Cerebrospinal Fluid Cachectin/Tumor Necrosis Factor-α and Platelet-Activating Factor Concentrations and Severity of Bacterial Meningitis in Children

In prospective studies, tumor necrosis factor (TNFα) was detected in cerebrospinal fluid (CSF) of 33 of 38 children with bacterial meningitis (BM) but in none of 15 with viral meningitisZencephalitis P < .001). BM CSF TNFα (25,500 pgZml) correlated with CSF bacterial density (P < .01), CSF pro...

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Veröffentlicht in:	The Journal of infectious diseases 1990-07, Vol.162 (1), p.139-147
Hauptverfasser:	Arditi, Moshe, Manogue, Kirk R., Caplan, Michael, Yogev, Ram
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Antibiotics Bacteria - growth & development Bacterial diseases Bacterial meningitis Biological and medical sciences Cerebrospinal fluid Cerebrospinal Fluid - microbiology Cerebrospinal Fluid Proteins - cerebrospinal fluid Child Child, Preschool Children Endotoxins Endotoxins - cerebrospinal fluid Escherichia coli meningitis Haemophilus meningitis Humans Infant Infectious diseases Lipopolysaccharides - cerebrospinal fluid Major Articles Medical sciences Meningitis - cerebrospinal fluid Meningitis - complications Meningitis, Haemophilus - cerebrospinal fluid Meningitis, Haemophilus - complications Platelet Activating Factor - cerebrospinal fluid Pneumococcal meningitis Prospective Studies Seizures - etiology Tumor Necrosis Factor-alpha - cerebrospinal fluid Tumor necrosis factors Viral meningitis
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