Plasma thiamine deficiency associated with Alzheimer's disease but not Parkinson's disease
In this study we compared plasma and erythrocyte thiamine levels in a group of patients with idiopathic Parkinson's Disease (iPD) to a group of patients with probable Alzheimer's Disease (pAD). pAD patients had significantly lower plasma thiamine levels (raw and z-score) than iPD patients....
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| Veröffentlicht in: | Metabolic brain disease 1998-03, Vol.13 (1), p.43-54 |
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| container_title | Metabolic brain disease |
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| creator | Gold, M Hauser, R A Chen, M F |
| description | In this study we compared plasma and erythrocyte thiamine levels in a group of patients with idiopathic Parkinson's Disease (iPD) to a group of patients with probable Alzheimer's Disease (pAD). pAD patients had significantly lower plasma thiamine levels (raw and z-score) than iPD patients. A significantly higher number of pAD patients had plasma thiamine deficiencies than iPD patients. The demographics of our patient groups were similar to those reported by other investigators, making age, sex and nutritional status unlikely explanations for our findings. These results suggest that plasma thiamine deficiency is associated with pAD but not with iPD. |
| doi_str_mv | 10.1023/A:1020678912330 |
| format | Article |
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A significantly higher number of pAD patients had plasma thiamine deficiencies than iPD patients. The demographics of our patient groups were similar to those reported by other investigators, making age, sex and nutritional status unlikely explanations for our findings. These results suggest that plasma thiamine deficiency is associated with pAD but not with iPD.</description><identifier>ISSN: 0885-7490</identifier><identifier>DOI: 10.1023/A:1020678912330</identifier><identifier>PMID: 9570639</identifier><language>eng</language><publisher>United States</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Alzheimer Disease - blood ; Female ; Humans ; Male ; Middle Aged ; Parkinson Disease - blood ; Sex Factors ; Thiamine - blood ; Thiamine Deficiency - blood</subject><ispartof>Metabolic brain disease, 1998-03, Vol.13 (1), p.43-54</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c329t-a83e48986c0773c9ef7b8782201173439bc98d070c6397c49d1629729e6474d43</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9570639$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gold, M</creatorcontrib><creatorcontrib>Hauser, R A</creatorcontrib><creatorcontrib>Chen, M F</creatorcontrib><title>Plasma thiamine deficiency associated with Alzheimer's disease but not Parkinson's disease</title><title>Metabolic brain disease</title><addtitle>Metab Brain Dis</addtitle><description>In this study we compared plasma and erythrocyte thiamine levels in a group of patients with idiopathic Parkinson's Disease (iPD) to a group of patients with probable Alzheimer's Disease (pAD). pAD patients had significantly lower plasma thiamine levels (raw and z-score) than iPD patients. A significantly higher number of pAD patients had plasma thiamine deficiencies than iPD patients. The demographics of our patient groups were similar to those reported by other investigators, making age, sex and nutritional status unlikely explanations for our findings. 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| fulltext | fulltext |
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| ispartof | Metabolic brain disease, 1998-03, Vol.13 (1), p.43-54 |
| issn | 0885-7490 |
| language | eng |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Adult Aged Aged, 80 and over Alzheimer Disease - blood Female Humans Male Middle Aged Parkinson Disease - blood Sex Factors Thiamine - blood Thiamine Deficiency - blood |
| title | Plasma thiamine deficiency associated with Alzheimer's disease but not Parkinson's disease |
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