Lack of antiviral effect of amantadine in Borna disease virus infection

The antiviral effect of amantadine (1-aminoadamantane) was tested in vitro as well as in vivo. Treatment of persistently Borna disease virus (BDV)-infected cell lines of different origin and for various length of time did not result in a general reduction of virus titer or clearance of virus from in...

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Veröffentlicht in:	Medical microbiology and immunology 1998-03, Vol.186 (4), p.195-200
Hauptverfasser:	STITZ, L, PLANZ, O, BILZER, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Amantadine - blood Amantadine - pharmacology Amantadine - therapeutic use Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Antiviral Agents - pharmacology Antiviral Agents - therapeutic use Biological and medical sciences Borna Disease - drug therapy Borna Disease - pathology Borna Disease - virology Borna disease virus - drug effects Borna disease virus - physiology Brain - pathology Cell Line Dogs Encephalitis, Viral - drug therapy Encephalitis, Viral - pathology Encephalitis, Viral - virology Female Guinea Pigs Humans Medical sciences Pharmacology. Drug treatments Rats Rats, Inbred Lew Virus Replication - drug effects
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