Subgingival controlled release of antimicrobial agents in the treatment of periodontal disease
Local drug delivery of antimicrobics by sustained release delivery systems can be used to treat periodontal disease. Advantages of these systems may include biodegradation of the system, maintaining high levels of antibiotic in the gingival crevicular fluid (GCF) for a sustained period of time and e...
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| Veröffentlicht in: | International journal of antimicrobial agents 1998-02, Vol.9 (4), p.239-253 |
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| container_end_page | 253 |
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| container_title | International journal of antimicrobial agents |
| container_volume | 9 |
| creator | SOUTHARD, G. L GODOWSKI, K. C |
| description | Local drug delivery of antimicrobics by sustained release delivery systems can be used to treat periodontal disease. Advantages of these systems may include biodegradation of the system, maintaining high levels of antibiotic in the gingival crevicular fluid (GCF) for a sustained period of time and ease of use with high patient acceptance. This review will identify human in vivo clinical and microbiological studies. Sustained release formulations, application methods, clinical results and microbiological effects are discussed. |
| doi_str_mv | 10.1016/S0924-8579(98)00004-1 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0924-8579 |
| ispartof | International journal of antimicrobial agents, 1998-02, Vol.9 (4), p.239-253 |
| issn | 0924-8579 1872-7913 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Anti-Infective Agents - administration & dosage Anti-Infective Agents - pharmacokinetics Anti-Infective Agents - therapeutic use Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Clinical Trials as Topic Delayed-Action Preparations Gingiva Gingival Crevicular Fluid - metabolism Humans Medical sciences Periodontal Diseases - drug therapy Pharmacology. Drug treatments |
| title | Subgingival controlled release of antimicrobial agents in the treatment of periodontal disease |
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