Anti-complementary and hypoglycemic activities of the glycans from the seeds of Malva verticillata
Abstract Seven polysaccharides and peptidoglycans obtained from the seeds ofMALVA VERTICILLATA were tested for anti-complementary activity. Remarkable activities were observed for MVS-I and MVS-IIA. The former is mainly composed of β-1,3-linked D-glucan and of α-1,5-linked L-arabino-β-3,6-branched D...
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| Veröffentlicht in: | Planta medica 1990-04, Vol.56 (2), p.168-170 |
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| creator | Tomoda, M Shimizu, N Gonda, R Kanari, M Yamada, H Hikino, H |
| description | Abstract
Seven polysaccharides and peptidoglycans obtained from the seeds ofMALVA VERTICILLATA were tested for anti-complementary activity. Remarkable activities were observed for MVS-I and MVS-IIA. The former is mainly composed of β-1,3-linked D-glucan and of α-1,5-linked L-arabino-β-3,6-branched D-galactan, and the latter is essentially α-1,5-linkedL-arabino-β-3,6-branched D-galactan. Further, considerable activities were observed for MVS-IIIA and MVS-IVA. Both glycans possess arabino-3,6-galactan moieties accompanying α-1,3-linked L-arabinopyranosyl, β-1,4-linked D-xylosyl, and α-1,4-linked D-galacturonic acid units. In addition, the major neutral polysaccharide (MVS-I), the major peptidoglycan (MVS-V), and the polysaccharide-rich fraction (MVS-V-CH) obtained from MVS-V were tested for hypoglycemic activity. MVS-I especially showed remarkable activity, and MVS-V-CH also exhibited significant activity. From the viewpoint of structural features, the latter belongs to pectic substances. |
| doi_str_mv | 10.1055/s-2006-960917 |
| format | Article |
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Seven polysaccharides and peptidoglycans obtained from the seeds ofMALVA VERTICILLATA were tested for anti-complementary activity. Remarkable activities were observed for MVS-I and MVS-IIA. The former is mainly composed of β-1,3-linked D-glucan and of α-1,5-linked L-arabino-β-3,6-branched D-galactan, and the latter is essentially α-1,5-linkedL-arabino-β-3,6-branched D-galactan. Further, considerable activities were observed for MVS-IIIA and MVS-IVA. Both glycans possess arabino-3,6-galactan moieties accompanying α-1,3-linked L-arabinopyranosyl, β-1,4-linked D-xylosyl, and α-1,4-linked D-galacturonic acid units. In addition, the major neutral polysaccharide (MVS-I), the major peptidoglycan (MVS-V), and the polysaccharide-rich fraction (MVS-V-CH) obtained from MVS-V were tested for hypoglycemic activity. MVS-I especially showed remarkable activity, and MVS-V-CH also exhibited significant activity. From the viewpoint of structural features, the latter belongs to pectic substances.</description><identifier>ISSN: 0032-0943</identifier><identifier>EISSN: 1439-0221</identifier><identifier>DOI: 10.1055/s-2006-960917</identifier><identifier>PMID: 2353063</identifier><identifier>CODEN: PLMEAA</identifier><language>eng</language><publisher>Stuttgart: Thieme</publisher><subject>Animals ; Biological and medical sciences ; Carbohydrate Sequence ; Complement Inactivator Proteins - isolation & purification ; Drugs, Chinese Herbal - pharmacology ; General pharmacology ; Humans ; hypoglycemic agents ; Hypoglycemic Agents - isolation & purification ; Male ; malva verticillata ; Medical sciences ; Mice ; Molecular Sequence Data ; peptidoglycans ; Pharmacognosy. Homeopathy. Health food ; Pharmacology. Drug treatments ; polysaccharides ; Polysaccharides - isolation & purification ; Polysaccharides - pharmacology ; seeds ; Seeds - analysis</subject><ispartof>Planta medica, 1990-04, Vol.56 (2), p.168-170</ispartof><rights>Georg Thieme Verlag Stuttgart · New York</rights><rights>1990 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2937-2cbabf693498afa5142d7a332f725ba8aaeb4ec80b1e0944222e8bc9ce4b1fa83</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2006-960917.pdf$$EPDF$$P50$$Gthieme$$H</linktopdf><link.rule.ids>314,776,780,3004,3005,27901,27902,54534</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=6846109$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2353063$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tomoda, M</creatorcontrib><creatorcontrib>Shimizu, N</creatorcontrib><creatorcontrib>Gonda, R</creatorcontrib><creatorcontrib>Kanari, M</creatorcontrib><creatorcontrib>Yamada, H</creatorcontrib><creatorcontrib>Hikino, H</creatorcontrib><title>Anti-complementary and hypoglycemic activities of the glycans from the seeds of Malva verticillata</title><title>Planta medica</title><addtitle>Planta Med</addtitle><description>Abstract
Seven polysaccharides and peptidoglycans obtained from the seeds ofMALVA VERTICILLATA were tested for anti-complementary activity. Remarkable activities were observed for MVS-I and MVS-IIA. The former is mainly composed of β-1,3-linked D-glucan and of α-1,5-linked L-arabino-β-3,6-branched D-galactan, and the latter is essentially α-1,5-linkedL-arabino-β-3,6-branched D-galactan. Further, considerable activities were observed for MVS-IIIA and MVS-IVA. Both glycans possess arabino-3,6-galactan moieties accompanying α-1,3-linked L-arabinopyranosyl, β-1,4-linked D-xylosyl, and α-1,4-linked D-galacturonic acid units. In addition, the major neutral polysaccharide (MVS-I), the major peptidoglycan (MVS-V), and the polysaccharide-rich fraction (MVS-V-CH) obtained from MVS-V were tested for hypoglycemic activity. MVS-I especially showed remarkable activity, and MVS-V-CH also exhibited significant activity. From the viewpoint of structural features, the latter belongs to pectic substances.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Carbohydrate Sequence</subject><subject>Complement Inactivator Proteins - isolation & purification</subject><subject>Drugs, Chinese Herbal - pharmacology</subject><subject>General pharmacology</subject><subject>Humans</subject><subject>hypoglycemic agents</subject><subject>Hypoglycemic Agents - isolation & purification</subject><subject>Male</subject><subject>malva verticillata</subject><subject>Medical sciences</subject><subject>Mice</subject><subject>Molecular Sequence Data</subject><subject>peptidoglycans</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacology. Drug treatments</subject><subject>polysaccharides</subject><subject>Polysaccharides - isolation & purification</subject><subject>Polysaccharides - pharmacology</subject><subject>seeds</subject><subject>Seeds - analysis</subject><issn>0032-0943</issn><issn>1439-0221</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kElrHDEQRkWIcSa2jzmG9MHkFCWlpRcdjckGNjkkPouSpuSR6WUi9QzMv4_GPfiWgxDoe3yqeoy9E_BZQF1_yVwCNNw0YET7iq2EVoaDlOI1WwEoycFo9Ya9zfkJQGgDcM7OpaoVNGrF3M04R-6nYdvTQOOM6VDhuK42h-302B88DdFX6Oe4j3OkXE2hmjdUHSMccxXSNDw_ZKL1c3qP_R6rPaU5-tj3OOMlOwvYZ7o63Rfs4dvXP7c_-N2v7z9vb-64l0a1XHqHLjRGadNhwFpouW5RKRlaWTvsEMlp8h04QWUlLaWkznnjSTsRsFMX7OPSu03T3x3l2Q4xeyozjDTtsm1NJ7tyCsgX0Kcp50TBblMcyuZWgD06tdkendrFaeHfn4p3bqD1C32SWPLrU47ZYx8Sjj7mF6zpdCPAFOzTgs2bWFzbp2mXxiLkv79-WPCAk8XHVBoffksQCkQrTdtq9Q-Depa5</recordid><startdate>199004</startdate><enddate>199004</enddate><creator>Tomoda, M</creator><creator>Shimizu, N</creator><creator>Gonda, R</creator><creator>Kanari, M</creator><creator>Yamada, H</creator><creator>Hikino, H</creator><general>Thieme</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199004</creationdate><title>Anti-complementary and hypoglycemic activities of the glycans from the seeds of Malva verticillata</title><author>Tomoda, M ; Shimizu, N ; Gonda, R ; Kanari, M ; Yamada, H ; Hikino, H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2937-2cbabf693498afa5142d7a332f725ba8aaeb4ec80b1e0944222e8bc9ce4b1fa83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Carbohydrate Sequence</topic><topic>Complement Inactivator Proteins - isolation & purification</topic><topic>Drugs, Chinese Herbal - pharmacology</topic><topic>General pharmacology</topic><topic>Humans</topic><topic>hypoglycemic agents</topic><topic>Hypoglycemic Agents - isolation & purification</topic><topic>Male</topic><topic>malva verticillata</topic><topic>Medical sciences</topic><topic>Mice</topic><topic>Molecular Sequence Data</topic><topic>peptidoglycans</topic><topic>Pharmacognosy. Homeopathy. Health food</topic><topic>Pharmacology. Drug treatments</topic><topic>polysaccharides</topic><topic>Polysaccharides - isolation & purification</topic><topic>Polysaccharides - pharmacology</topic><topic>seeds</topic><topic>Seeds - analysis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tomoda, M</creatorcontrib><creatorcontrib>Shimizu, N</creatorcontrib><creatorcontrib>Gonda, R</creatorcontrib><creatorcontrib>Kanari, M</creatorcontrib><creatorcontrib>Yamada, H</creatorcontrib><creatorcontrib>Hikino, H</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Planta medica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tomoda, M</au><au>Shimizu, N</au><au>Gonda, R</au><au>Kanari, M</au><au>Yamada, H</au><au>Hikino, H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Anti-complementary and hypoglycemic activities of the glycans from the seeds of Malva verticillata</atitle><jtitle>Planta medica</jtitle><addtitle>Planta Med</addtitle><date>1990-04</date><risdate>1990</risdate><volume>56</volume><issue>2</issue><spage>168</spage><epage>170</epage><pages>168-170</pages><issn>0032-0943</issn><eissn>1439-0221</eissn><coden>PLMEAA</coden><abstract>Abstract
Seven polysaccharides and peptidoglycans obtained from the seeds ofMALVA VERTICILLATA were tested for anti-complementary activity. Remarkable activities were observed for MVS-I and MVS-IIA. The former is mainly composed of β-1,3-linked D-glucan and of α-1,5-linked L-arabino-β-3,6-branched D-galactan, and the latter is essentially α-1,5-linkedL-arabino-β-3,6-branched D-galactan. Further, considerable activities were observed for MVS-IIIA and MVS-IVA. Both glycans possess arabino-3,6-galactan moieties accompanying α-1,3-linked L-arabinopyranosyl, β-1,4-linked D-xylosyl, and α-1,4-linked D-galacturonic acid units. In addition, the major neutral polysaccharide (MVS-I), the major peptidoglycan (MVS-V), and the polysaccharide-rich fraction (MVS-V-CH) obtained from MVS-V were tested for hypoglycemic activity. MVS-I especially showed remarkable activity, and MVS-V-CH also exhibited significant activity. From the viewpoint of structural features, the latter belongs to pectic substances.</abstract><cop>Stuttgart</cop><cop>New York, NY</cop><pub>Thieme</pub><pmid>2353063</pmid><doi>10.1055/s-2006-960917</doi><tpages>3</tpages></addata></record> |
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| subjects | Animals Biological and medical sciences Carbohydrate Sequence Complement Inactivator Proteins - isolation & purification Drugs, Chinese Herbal - pharmacology General pharmacology Humans hypoglycemic agents Hypoglycemic Agents - isolation & purification Male malva verticillata Medical sciences Mice Molecular Sequence Data peptidoglycans Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments polysaccharides Polysaccharides - isolation & purification Polysaccharides - pharmacology seeds Seeds - analysis |
| title | Anti-complementary and hypoglycemic activities of the glycans from the seeds of Malva verticillata |
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