Characterization of thyroid hormone sulfotransferases

Sulfation is an intriguing pathway of thyroid hormone metabolism since it facilitates the degradation of the hormone by the type I deiodinase (D1). This study reports the preliminary characterization of iodothyronine sulfotransferase activities of rat and human liver cytosol and recombinant rSULT1C1...

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Veröffentlicht in:	Chemico-biological interactions 1998-02, Vol.109 (1), p.279-291
Hauptverfasser:	Visser, Theo J, Kaptein, Ellen, Glatt, Hansruedi, Bartsch, Ingrid, Hagen, Maria, Coughtrie, Michael W.H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cytosol - enzymology Deiodination Enzyme Inhibitors - pharmacology Female Human Humans Iodothyronines Isoenzymes - metabolism Kinetics Liver Liver - enzymology Male Phenols Phenols - pharmacology Rat Rats Rats, Wistar Sulfates - metabolism Sulfation Sulfotransferase Sulfotransferases - antagonists & inhibitors Sulfotransferases - metabolism Thyroid hormone Thyroid Hormones - metabolism
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