Spironolactone and altizide used in combination with enalapril: Twenty-four-hour ambulatory recording of blood pressure
The addition of enalapril or acebutolol to a regimen of altizide + spironolactone in patients with moderate hypotension was investigated in a multicenter study of S3 patients. The patients underwent semiambulatory 24-hour blood pressure monitoring, especially to observe hypotensive episodes. In the...
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Veröffentlicht in: | The American journal of cardiology 1990-06, Vol.65 (23), p.K33-K35 |
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creator | Poncelet, Pascal Wehrten, Marie Pelletier, Bruno Capron, Michel-Hubert |
description | The addition of enalapril or acebutolol to a regimen of altizide + spironolactone in patients with moderate hypotension was investigated in a multicenter study of S3 patients. The patients underwent semiambulatory 24-hour blood pressure monitoring, especially to observe hypotensive episodes. In the 25 patients uncontrolled with altizide + spironolactone alone, enalapril and acebutolol were about equally effective in reducing blood pressure. The incidence of hypotension was low and comparable for both treatment groups, provided that the initial dose of angiotensin-converting enzyme inhibitor was low (5 mg). |
doi_str_mv | 10.1016/0002-9149(90)91275-B |
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The patients underwent semiambulatory 24-hour blood pressure monitoring, especially to observe hypotensive episodes. In the 25 patients uncontrolled with altizide + spironolactone alone, enalapril and acebutolol were about equally effective in reducing blood pressure. 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Drug treatments ; Randomized Controlled Trials as Topic ; Sodium Chloride Symporter Inhibitors - administration & dosage ; Sodium Chloride Symporter Inhibitors - therapeutic use ; Spironolactone - administration & dosage ; Spironolactone - therapeutic use ; Sulfonamides - administration & dosage ; Sulfonamides - therapeutic use</subject><ispartof>The American journal of cardiology, 1990-06, Vol.65 (23), p.K33-K35</ispartof><rights>1990</rights><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c251t-79f67332e56b1ac5380b484cf97a27f2f2dadb9bc712e4638d7fe71fda2d8baf3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0002-9149(90)91275-B$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>309,310,314,777,781,786,787,3537,23911,23912,25121,27905,27906,45976</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19341924$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2191587$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Poncelet, Pascal</creatorcontrib><creatorcontrib>Wehrten, Marie</creatorcontrib><creatorcontrib>Pelletier, Bruno</creatorcontrib><creatorcontrib>Capron, Michel-Hubert</creatorcontrib><title>Spironolactone and altizide used in combination with enalapril: Twenty-four-hour ambulatory recording of blood pressure</title><title>The American journal of cardiology</title><addtitle>Am J Cardiol</addtitle><description>The addition of enalapril or acebutolol to a regimen of altizide + spironolactone in patients with moderate hypotension was investigated in a multicenter study of S3 patients. The patients underwent semiambulatory 24-hour blood pressure monitoring, especially to observe hypotensive episodes. In the 25 patients uncontrolled with altizide + spironolactone alone, enalapril and acebutolol were about equally effective in reducing blood pressure. The incidence of hypotension was low and comparable for both treatment groups, provided that the initial dose of angiotensin-converting enzyme inhibitor was low (5 mg).</description><subject>Acebutolol - administration & dosage</subject><subject>Acebutolol - therapeutic use</subject><subject>Antihypertensive agents</subject><subject>Benzothiadiazines</subject><subject>Biological and medical sciences</subject><subject>Blood Pressure - drug effects</subject><subject>Cardiovascular system</subject><subject>Diuretics</subject><subject>Drug Therapy, Combination</subject><subject>Enalapril - administration & dosage</subject><subject>Enalapril - adverse effects</subject><subject>Enalapril - therapeutic use</subject><subject>Female</subject><subject>Humans</subject><subject>Hypertension - drug therapy</subject><subject>Hypertension - physiopathology</subject><subject>Hypotension - diagnosis</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Monitoring, Physiologic</subject><subject>Multicenter Studies as Topic</subject><subject>Pharmacology. Drug treatments</subject><subject>Randomized Controlled Trials as Topic</subject><subject>Sodium Chloride Symporter Inhibitors - administration & dosage</subject><subject>Sodium Chloride Symporter Inhibitors - therapeutic use</subject><subject>Spironolactone - administration & dosage</subject><subject>Spironolactone - therapeutic use</subject><subject>Sulfonamides - administration & dosage</subject><subject>Sulfonamides - therapeutic use</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE2LFDEQhoMo67j6DxRyUfTQ2kl_pLMHwV38ggUPrudQnVTcSDoZk7TD-OvNOMN685Ii1FMvVQ8hT1n7mrVsfNO2LW8k6-VL2b6SjIuhubxHNmwSsmGSdffJ5g55SB7l_KN-GRvGM3LGKzBMYkN2X7cuxRA96BIDUgiGgi_utzNI14yGukB1XGYXoLgY6M6VW4oBPGyT8xf0Zoeh7Bsb19Tc1ofCMq8eSkx7mlDHZFz4TqOls4_R0G3CnNeEj8kDCz7jk1M9J98-vL-5-tRcf_n4-erddaP5wEojpB1F13EcxpmBHrqpnfup11YK4MJyyw2YWc5aMI792E1GWBTMGuBmmsF25-TFMXeb4s8Vc1GLyxq9h4BxzUrIiQ_dICvYH0GdYs4Jrar3LZD2irXq4FsdZKqDTCVb9de3uqxjz07567yguRs6Ca7956c-ZA3eJgja5X_ZsuuZ5H3l3h45rDJ-OUwqa4dBo3HVYlEmuv8v8gctvp9q</recordid><startdate>19900619</startdate><enddate>19900619</enddate><creator>Poncelet, Pascal</creator><creator>Wehrten, Marie</creator><creator>Pelletier, Bruno</creator><creator>Capron, Michel-Hubert</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19900619</creationdate><title>Spironolactone and altizide used in combination with enalapril: Twenty-four-hour ambulatory recording of blood pressure</title><author>Poncelet, Pascal ; Wehrten, Marie ; Pelletier, Bruno ; Capron, Michel-Hubert</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c251t-79f67332e56b1ac5380b484cf97a27f2f2dadb9bc712e4638d7fe71fda2d8baf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Acebutolol - administration & dosage</topic><topic>Acebutolol - therapeutic use</topic><topic>Antihypertensive agents</topic><topic>Benzothiadiazines</topic><topic>Biological and medical sciences</topic><topic>Blood Pressure - drug effects</topic><topic>Cardiovascular system</topic><topic>Diuretics</topic><topic>Drug Therapy, Combination</topic><topic>Enalapril - administration & dosage</topic><topic>Enalapril - adverse effects</topic><topic>Enalapril - therapeutic use</topic><topic>Female</topic><topic>Humans</topic><topic>Hypertension - drug therapy</topic><topic>Hypertension - physiopathology</topic><topic>Hypotension - diagnosis</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Monitoring, Physiologic</topic><topic>Multicenter Studies as Topic</topic><topic>Pharmacology. Drug treatments</topic><topic>Randomized Controlled Trials as Topic</topic><topic>Sodium Chloride Symporter Inhibitors - administration & dosage</topic><topic>Sodium Chloride Symporter Inhibitors - therapeutic use</topic><topic>Spironolactone - administration & dosage</topic><topic>Spironolactone - therapeutic use</topic><topic>Sulfonamides - administration & dosage</topic><topic>Sulfonamides - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Poncelet, Pascal</creatorcontrib><creatorcontrib>Wehrten, Marie</creatorcontrib><creatorcontrib>Pelletier, Bruno</creatorcontrib><creatorcontrib>Capron, Michel-Hubert</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Poncelet, Pascal</au><au>Wehrten, Marie</au><au>Pelletier, Bruno</au><au>Capron, Michel-Hubert</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Spironolactone and altizide used in combination with enalapril: Twenty-four-hour ambulatory recording of blood pressure</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>1990-06-19</date><risdate>1990</risdate><volume>65</volume><issue>23</issue><spage>K33</spage><epage>K35</epage><pages>K33-K35</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>The addition of enalapril or acebutolol to a regimen of altizide + spironolactone in patients with moderate hypotension was investigated in a multicenter study of S3 patients. The patients underwent semiambulatory 24-hour blood pressure monitoring, especially to observe hypotensive episodes. In the 25 patients uncontrolled with altizide + spironolactone alone, enalapril and acebutolol were about equally effective in reducing blood pressure. The incidence of hypotension was low and comparable for both treatment groups, provided that the initial dose of angiotensin-converting enzyme inhibitor was low (5 mg).</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>2191587</pmid><doi>10.1016/0002-9149(90)91275-B</doi></addata></record> |
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subjects | Acebutolol - administration & dosage Acebutolol - therapeutic use Antihypertensive agents Benzothiadiazines Biological and medical sciences Blood Pressure - drug effects Cardiovascular system Diuretics Drug Therapy, Combination Enalapril - administration & dosage Enalapril - adverse effects Enalapril - therapeutic use Female Humans Hypertension - drug therapy Hypertension - physiopathology Hypotension - diagnosis Male Medical sciences Middle Aged Monitoring, Physiologic Multicenter Studies as Topic Pharmacology. Drug treatments Randomized Controlled Trials as Topic Sodium Chloride Symporter Inhibitors - administration & dosage Sodium Chloride Symporter Inhibitors - therapeutic use Spironolactone - administration & dosage Spironolactone - therapeutic use Sulfonamides - administration & dosage Sulfonamides - therapeutic use |
title | Spironolactone and altizide used in combination with enalapril: Twenty-four-hour ambulatory recording of blood pressure |
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