Membrane-Induced Secondary Structures of Neuropeptides:  A Comparison of the Solution Conformations Adopted by Agonists and Antagonists of the Mammalian Tachykinin NK1 Receptor

We present what we believe to be the first documented example of an inducement of distinctly different secondary structure types onto agonists and antagonists selective for the same G-coupled protein receptor using the same membrane-model matrix wherein the induced structures are consistent with tho...

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Veröffentlicht in:Journal of medicinal chemistry 1998-04, Vol.41 (9), p.1497-1506
Hauptverfasser: Whitehead, Tracy L, McNair, Sharon D, Hadden, Chad E, Young, John K, Hicks, Rickey P
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Sprache:eng
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