gamma delta T-cell receptor-positive T-cell clones derived from human heart transplants do not show donor-specific cytotoxicity
gamma delta T-cell receptor-positive T-cell clones were obtained from three endomyocardial biopsies taken from two patients. Clones obtained from two biopsies from patient A, one taken during rejection and one after resolution of this rejection, were WT31-, 11F2+, Ti gamma A-, delta TcS1+. Clones fr...
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| Veröffentlicht in: | Human immunology 1990-06, Vol.28 (2), p.170-174 |
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| container_end_page | 174 |
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| container_issue | 2 |
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| container_title | Human immunology |
| container_volume | 28 |
| creator | Jutte, N H Vandekerckhove, B A Vaessen, L M Ouwehand, A J Baan, C C Bos, E Claas, F H Weimar, W |
| description | gamma delta T-cell receptor-positive T-cell clones were obtained from three endomyocardial biopsies taken from two patients. Clones obtained from two biopsies from patient A, one taken during rejection and one after resolution of this rejection, were WT31-, 11F2+, Ti gamma A-, delta TcS1+. Clones from patient B grown from a biopsy without histologic signs of rejection were either WT31-, 11F2+, Ti gamma A+, delta TcS1-, or WT31+. All gamma delta T-cell receptor-positive clones had cytolytic potential but did not demonstrate donor-specific lysis. |
| doi_str_mv | 10.1016/0198-8859(90)90015-H |
| format | Article |
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Clones obtained from two biopsies from patient A, one taken during rejection and one after resolution of this rejection, were WT31-, 11F2+, Ti gamma A-, delta TcS1+. Clones from patient B grown from a biopsy without histologic signs of rejection were either WT31-, 11F2+, Ti gamma A+, delta TcS1-, or WT31+. All gamma delta T-cell receptor-positive clones had cytolytic potential but did not demonstrate donor-specific lysis.</description><identifier>ISSN: 0198-8859</identifier><identifier>DOI: 10.1016/0198-8859(90)90015-H</identifier><identifier>PMID: 2141011</identifier><language>eng</language><publisher>United States</publisher><subject>Biopsy ; Clone Cells ; Cytotoxicity, Immunologic - immunology ; Graft Rejection - immunology ; Heart Transplantation - immunology ; Humans ; Myocardium - cytology ; Phenotype ; Receptors, Antigen, T-Cell - physiology ; Receptors, Antigen, T-Cell, gamma-delta ; T-Lymphocytes - immunology</subject><ispartof>Human immunology, 1990-06, Vol.28 (2), p.170-174</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2141011$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jutte, N H</creatorcontrib><creatorcontrib>Vandekerckhove, B A</creatorcontrib><creatorcontrib>Vaessen, L M</creatorcontrib><creatorcontrib>Ouwehand, A J</creatorcontrib><creatorcontrib>Baan, C C</creatorcontrib><creatorcontrib>Bos, E</creatorcontrib><creatorcontrib>Claas, F H</creatorcontrib><creatorcontrib>Weimar, W</creatorcontrib><title>gamma delta T-cell receptor-positive T-cell clones derived from human heart transplants do not show donor-specific cytotoxicity</title><title>Human immunology</title><addtitle>Hum Immunol</addtitle><description>gamma delta T-cell receptor-positive T-cell clones were obtained from three endomyocardial biopsies taken from two patients. Clones obtained from two biopsies from patient A, one taken during rejection and one after resolution of this rejection, were WT31-, 11F2+, Ti gamma A-, delta TcS1+. Clones from patient B grown from a biopsy without histologic signs of rejection were either WT31-, 11F2+, Ti gamma A+, delta TcS1-, or WT31+. All gamma delta T-cell receptor-positive clones had cytolytic potential but did not demonstrate donor-specific lysis.</description><subject>Biopsy</subject><subject>Clone Cells</subject><subject>Cytotoxicity, Immunologic - immunology</subject><subject>Graft Rejection - immunology</subject><subject>Heart Transplantation - immunology</subject><subject>Humans</subject><subject>Myocardium - cytology</subject><subject>Phenotype</subject><subject>Receptors, Antigen, T-Cell - physiology</subject><subject>Receptors, Antigen, T-Cell, gamma-delta</subject><subject>T-Lymphocytes - immunology</subject><issn>0198-8859</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkD9PwzAQxT2ASil8A5A8IRgC5zj-N6IKKBISS5kjx3GoURIH2wE68dUJorAy3end7z3pHUInBC4JEH4FRMlMSqbOFVwoAMKy1R6a_8kH6DDGFwAQIIoZmuWkmHxkjj6fdddpXNs2abzOjG1bHKyxQ_IhG3x0yb3Z34NpfW_jBIdJrHETfIc3Y6d7vLE6JJyC7uPQ6j5NkMe9Tzhu_Pu091NaHKxxjTPYbJNP_sMZl7ZHaL_RbbTHu7lAT7c36-Uqe3i8u19eP2QD4SplNVWmNgSUrpiCnLEGLJCc0yIHwQqplRCUqAoMF9QqyTkzvKoKBo2kuajoAp395A7Bv442prJz8buU7q0fYymUJCqn5F-QcCCFYGwCT3fgWHW2LofgOh225e619AtGmHrc</recordid><startdate>19900601</startdate><enddate>19900601</enddate><creator>Jutte, N H</creator><creator>Vandekerckhove, B A</creator><creator>Vaessen, L M</creator><creator>Ouwehand, A J</creator><creator>Baan, C C</creator><creator>Bos, E</creator><creator>Claas, F H</creator><creator>Weimar, W</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>19900601</creationdate><title>gamma delta T-cell receptor-positive T-cell clones derived from human heart transplants do not show donor-specific cytotoxicity</title><author>Jutte, N H ; Vandekerckhove, B A ; Vaessen, L M ; Ouwehand, A J ; Baan, C C ; Bos, E ; Claas, F H ; Weimar, W</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p169t-d39cdc109ab590255f0e012634207548a977319b0c673e98665c6bb450f8327b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Biopsy</topic><topic>Clone Cells</topic><topic>Cytotoxicity, Immunologic - immunology</topic><topic>Graft Rejection - immunology</topic><topic>Heart Transplantation - immunology</topic><topic>Humans</topic><topic>Myocardium - cytology</topic><topic>Phenotype</topic><topic>Receptors, Antigen, T-Cell - physiology</topic><topic>Receptors, Antigen, T-Cell, gamma-delta</topic><topic>T-Lymphocytes - immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jutte, N H</creatorcontrib><creatorcontrib>Vandekerckhove, B A</creatorcontrib><creatorcontrib>Vaessen, L M</creatorcontrib><creatorcontrib>Ouwehand, A J</creatorcontrib><creatorcontrib>Baan, C C</creatorcontrib><creatorcontrib>Bos, E</creatorcontrib><creatorcontrib>Claas, F H</creatorcontrib><creatorcontrib>Weimar, W</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Human immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jutte, N H</au><au>Vandekerckhove, B A</au><au>Vaessen, L M</au><au>Ouwehand, A J</au><au>Baan, C C</au><au>Bos, E</au><au>Claas, F H</au><au>Weimar, W</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>gamma delta T-cell receptor-positive T-cell clones derived from human heart transplants do not show donor-specific cytotoxicity</atitle><jtitle>Human immunology</jtitle><addtitle>Hum Immunol</addtitle><date>1990-06-01</date><risdate>1990</risdate><volume>28</volume><issue>2</issue><spage>170</spage><epage>174</epage><pages>170-174</pages><issn>0198-8859</issn><abstract>gamma delta T-cell receptor-positive T-cell clones were obtained from three endomyocardial biopsies taken from two patients. Clones obtained from two biopsies from patient A, one taken during rejection and one after resolution of this rejection, were WT31-, 11F2+, Ti gamma A-, delta TcS1+. Clones from patient B grown from a biopsy without histologic signs of rejection were either WT31-, 11F2+, Ti gamma A+, delta TcS1-, or WT31+. All gamma delta T-cell receptor-positive clones had cytolytic potential but did not demonstrate donor-specific lysis.</abstract><cop>United States</cop><pmid>2141011</pmid><doi>10.1016/0198-8859(90)90015-H</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0198-8859 |
| ispartof | Human immunology, 1990-06, Vol.28 (2), p.170-174 |
| issn | 0198-8859 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79819231 |
| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Biopsy Clone Cells Cytotoxicity, Immunologic - immunology Graft Rejection - immunology Heart Transplantation - immunology Humans Myocardium - cytology Phenotype Receptors, Antigen, T-Cell - physiology Receptors, Antigen, T-Cell, gamma-delta T-Lymphocytes - immunology |
| title | gamma delta T-cell receptor-positive T-cell clones derived from human heart transplants do not show donor-specific cytotoxicity |
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