Signal transduction by the c-Jun N-terminal kinase (JNK) — from inflammation to development

The c-Jun amino-terminal kinase (JNK) group of MAP kinases has been identified in mammals and insects. JNK is activated by exposure of cells to cytokines or environmental stress, indicating that this signaling pathway may contribute to inflammatory responses. Genetic and biochemical studies demonstr...

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Veröffentlicht in:	Current opinion in cell biology 1998-04, Vol.10 (2), p.205-219
Hauptverfasser:	Ip, Y Tony, Davis, Roger J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium-Calmodulin-Dependent Protein Kinases - physiology Embryo, Mammalian - enzymology Embryo, Mammalian - physiology Embryo, Nonmammalian - enzymology Embryo, Nonmammalian - physiology Humans Inflammation - enzymology Inflammation - metabolism Inflammation - physiopathology JNK Mitogen-Activated Protein Kinases Mitogen-Activated Protein Kinases Morphogenesis - physiology Signal Transduction - physiology
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