Carcinomas of the breast showing myoepithelial cell differentiation : A review of the literature
Myoepithelial cells are normally located between the epithelial cells and the basal lamina of secretory elements of exocrine glands. Their role in the histogenesis of breast tumours has been studied extensively, and a definite differentiation towards myoepithelial cells has been demonstrated in aden...
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| Veröffentlicht in: | Virchows Archiv : an international journal of pathology 1998-04, Vol.432 (4), p.303-310 |
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| container_title | Virchows Archiv : an international journal of pathology |
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| creator | FOSCHINI, M. P EUSEBI, V |
| description | Myoepithelial cells are normally located between the epithelial cells and the basal lamina of secretory elements of exocrine glands. Their role in the histogenesis of breast tumours has been studied extensively, and a definite differentiation towards myoepithelial cells has been demonstrated in adenoid cystic carcinoma, adenomyoepithelioma, low-grade adenosquamous (syringomatous) carcinoma, pure malignant myoepithelioma and poorly differentiated myoepithelial-rich breast carcinoma. All these tumours are of low malignancy, with the exception of malignant myoepithelioma and poorly differentiated myoepithelial-rich carcinoma. When a low-grade tumour is associated with a spindle cell component, distant metastases must be expected. Pure malignant myoepithelioma shows morphological and clinical features similar to those of monophasic sarcomatoid carcinomas, and it is possible that this last tumour is linked histogenetically to sarcomatoid carcinomas. |
| doi_str_mv | 10.1007/s004280050170 |
| format | Article |
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Pure malignant myoepithelioma shows morphological and clinical features similar to those of monophasic sarcomatoid carcinomas, and it is possible that this last tumour is linked histogenetically to sarcomatoid carcinomas.</description><identifier>ISSN: 0945-6317</identifier><identifier>EISSN: 1432-2307</identifier><identifier>DOI: 10.1007/s004280050170</identifier><identifier>PMID: 9565338</identifier><language>eng</language><publisher>Berlin: Springer</publisher><subject>Actins - analysis ; Adenomyoma - pathology ; Adult ; Aged ; Aged, 80 and over ; Biological and medical sciences ; Breast Neoplasms - chemistry ; Breast Neoplasms - pathology ; Breast Neoplasms, Male - pathology ; Carcinoma - chemistry ; Carcinoma - pathology ; Carcinoma, Adenoid Cystic - chemistry ; Carcinoma, Adenoid Cystic - pathology ; Carcinoma, Adenosquamous - pathology ; Child, Preschool ; Collagen - analysis ; Epithelial Cells - cytology ; Female ; Gynecology. Andrology. 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P</creatorcontrib><creatorcontrib>EUSEBI, V</creatorcontrib><title>Carcinomas of the breast showing myoepithelial cell differentiation : A review of the literature</title><title>Virchows Archiv : an international journal of pathology</title><addtitle>Virchows Arch</addtitle><description>Myoepithelial cells are normally located between the epithelial cells and the basal lamina of secretory elements of exocrine glands. Their role in the histogenesis of breast tumours has been studied extensively, and a definite differentiation towards myoepithelial cells has been demonstrated in adenoid cystic carcinoma, adenomyoepithelioma, low-grade adenosquamous (syringomatous) carcinoma, pure malignant myoepithelioma and poorly differentiated myoepithelial-rich breast carcinoma. All these tumours are of low malignancy, with the exception of malignant myoepithelioma and poorly differentiated myoepithelial-rich carcinoma. When a low-grade tumour is associated with a spindle cell component, distant metastases must be expected. Pure malignant myoepithelioma shows morphological and clinical features similar to those of monophasic sarcomatoid carcinomas, and it is possible that this last tumour is linked histogenetically to sarcomatoid carcinomas.</description><subject>Actins - analysis</subject><subject>Adenomyoma - pathology</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Breast Neoplasms - chemistry</subject><subject>Breast Neoplasms - pathology</subject><subject>Breast Neoplasms, Male - pathology</subject><subject>Carcinoma - chemistry</subject><subject>Carcinoma - pathology</subject><subject>Carcinoma, Adenoid Cystic - chemistry</subject><subject>Carcinoma, Adenoid Cystic - pathology</subject><subject>Carcinoma, Adenosquamous - pathology</subject><subject>Child, Preschool</subject><subject>Collagen - analysis</subject><subject>Epithelial Cells - cytology</subject><subject>Female</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><subject>Male</subject><subject>Mammary gland diseases</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Muscle, Smooth - cytology</subject><subject>Myoepithelioma - pathology</subject><subject>Prognosis</subject><subject>Tumors</subject><issn>0945-6317</issn><issn>1432-2307</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kDtPwzAUhS0EKqUwMiJ5QGwBP-IXWxXxkiqxwByc5IYa5YXtUPXfE0RgusP36eici9A5JdeUEHUTCEmZJkQQqsgBWtKUs4Rxog7RkphUJJJTdYxOQvgghFFN5QItjJCCc71Eb5n1pev61gbc1zhuARcebIg4bPud695xu-9hcBNonG1wCU2DK1fX4KGLzkbXd_gWr7GHLwe7v4zGRfA2jh5O0VFtmwBn812h1_u7l-wx2Tw_PGXrTTJQqWKiJBWFYJIZM-2wtKg5kyWruNEm5cA01TxNrWFVYUAaywpuBDe14lMVRSRfoavf3MH3nyOEmLcu_LS1HfRjyJXRVGmWTuLFLI5FC1U-eNdav8_nl0z8cuY2lLapve1KF_41Rg0lgvJvXgVuvA</recordid><startdate>19980401</startdate><enddate>19980401</enddate><creator>FOSCHINI, M. 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P ; EUSEBI, V</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p167t-7615b526299017a1bf326c2d398943e2818344a92db9e69a2b39539f73ffe7063</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Actins - analysis</topic><topic>Adenomyoma - pathology</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Breast Neoplasms - chemistry</topic><topic>Breast Neoplasms - pathology</topic><topic>Breast Neoplasms, Male - pathology</topic><topic>Carcinoma - chemistry</topic><topic>Carcinoma - pathology</topic><topic>Carcinoma, Adenoid Cystic - chemistry</topic><topic>Carcinoma, Adenoid Cystic - pathology</topic><topic>Carcinoma, Adenosquamous - pathology</topic><topic>Child, Preschool</topic><topic>Collagen - analysis</topic><topic>Epithelial Cells - cytology</topic><topic>Female</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><topic>Male</topic><topic>Mammary gland diseases</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Muscle, Smooth - cytology</topic><topic>Myoepithelioma - pathology</topic><topic>Prognosis</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>FOSCHINI, M. P</creatorcontrib><creatorcontrib>EUSEBI, V</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Virchows Archiv : an international journal of pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>FOSCHINI, M. P</au><au>EUSEBI, V</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Carcinomas of the breast showing myoepithelial cell differentiation : A review of the literature</atitle><jtitle>Virchows Archiv : an international journal of pathology</jtitle><addtitle>Virchows Arch</addtitle><date>1998-04-01</date><risdate>1998</risdate><volume>432</volume><issue>4</issue><spage>303</spage><epage>310</epage><pages>303-310</pages><issn>0945-6317</issn><eissn>1432-2307</eissn><abstract>Myoepithelial cells are normally located between the epithelial cells and the basal lamina of secretory elements of exocrine glands. Their role in the histogenesis of breast tumours has been studied extensively, and a definite differentiation towards myoepithelial cells has been demonstrated in adenoid cystic carcinoma, adenomyoepithelioma, low-grade adenosquamous (syringomatous) carcinoma, pure malignant myoepithelioma and poorly differentiated myoepithelial-rich breast carcinoma. All these tumours are of low malignancy, with the exception of malignant myoepithelioma and poorly differentiated myoepithelial-rich carcinoma. When a low-grade tumour is associated with a spindle cell component, distant metastases must be expected. Pure malignant myoepithelioma shows morphological and clinical features similar to those of monophasic sarcomatoid carcinomas, and it is possible that this last tumour is linked histogenetically to sarcomatoid carcinomas.</abstract><cop>Berlin</cop><pub>Springer</pub><pmid>9565338</pmid><doi>10.1007/s004280050170</doi><tpages>8</tpages></addata></record> |
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| identifier | ISSN: 0945-6317 |
| ispartof | Virchows Archiv : an international journal of pathology, 1998-04, Vol.432 (4), p.303-310 |
| issn | 0945-6317 1432-2307 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals |
| subjects | Actins - analysis Adenomyoma - pathology Adult Aged Aged, 80 and over Biological and medical sciences Breast Neoplasms - chemistry Breast Neoplasms - pathology Breast Neoplasms, Male - pathology Carcinoma - chemistry Carcinoma - pathology Carcinoma, Adenoid Cystic - chemistry Carcinoma, Adenoid Cystic - pathology Carcinoma, Adenosquamous - pathology Child, Preschool Collagen - analysis Epithelial Cells - cytology Female Gynecology. Andrology. Obstetrics Humans Immunohistochemistry Male Mammary gland diseases Medical sciences Middle Aged Muscle, Smooth - cytology Myoepithelioma - pathology Prognosis Tumors |
| title | Carcinomas of the breast showing myoepithelial cell differentiation : A review of the literature |
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