Endemic infection with HTLV-IIB in Venezuelan Indians : Molecular characterization
The peripheral blood of 41 Yaruro and Guahibo Indians from Venezuela was examined for HTLV antibodies and DNA. Twenty-five samples (61%) were found to be infected with HTLV-IIB. The sensitivities of the serologic and DNA polymerase chain reaction (PCR) analyses were 80% and 96%, respectively. Epidem...
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| Veröffentlicht in: | Journal of acquired immune deficiency syndromes (1999) 1998-04, Vol.17 (5), p.458-464 |
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| container_title | Journal of acquired immune deficiency syndromes (1999) |
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| creator | LEON-PONTE, M ECHEVERRIA DE PEREZ, G BIANCO, N HENGST, J DUBE, S LOVE, J POIESZ, B. J |
| description | The peripheral blood of 41 Yaruro and Guahibo Indians from Venezuela was examined for HTLV antibodies and DNA. Twenty-five samples (61%) were found to be infected with HTLV-IIB. The sensitivities of the serologic and DNA polymerase chain reaction (PCR) analyses were 80% and 96%, respectively. Epidemiologic studies supported both sexual and perinatal transmission of the virus. Sequence analyses of the HTLV-IIB strains from these Indians indicate that they are unique relative to HTLV-II detected in other groups of humans. HTLV-IIB-G2 isolated from a Guahibo Indian is the most divergent HTLV-IIB strain relative to the prototype HTLV-II NRA. |
| doi_str_mv | 10.1097/00042560-199804150-00011 |
| format | Article |
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HTLV-IIB-G2 isolated from a Guahibo Indian is the most divergent HTLV-IIB strain relative to the prototype HTLV-II NRA.</description><identifier>ISSN: 1077-9450</identifier><identifier>ISSN: 1525-4135</identifier><identifier>EISSN: 2331-6993</identifier><identifier>EISSN: 1944-7884</identifier><identifier>DOI: 10.1097/00042560-199804150-00011</identifier><identifier>PMID: 9562049</identifier><language>eng</language><publisher>New York, NY: Raven Press</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; AIDS/HIV ; Animals ; Base Sequence ; Biological and medical sciences ; Cancer ; Cricetinae ; Disease Transmission, Infectious ; Genetics ; HTLV-II Infections - ethnology ; HTLV-II Infections - genetics ; HTLV-II Infections - transmission ; Human T-lymphotropic virus 2 - classification ; Human T-lymphotropic virus 2 - genetics ; Human viral diseases ; Humans ; Indians, South American ; Infections ; Infectious Disease Transmission, Vertical ; Infectious diseases ; Medical sciences ; Middle Aged ; Miscellaneous ; Molecular biology ; Molecular Sequence Data ; Native Americans ; Pedigree ; Phylogeny ; Polymerase Chain Reaction ; Prevalence ; Sequence Homology, Nucleic Acid ; Seroepidemiologic Studies ; Venezuela - epidemiology ; Viral diseases ; Viruses</subject><ispartof>Journal of acquired immune deficiency syndromes (1999), 1998-04, Vol.17 (5), p.458-464</ispartof><rights>1998 INIST-CNRS</rights><rights>Copyright Lippincott Williams & Wilkins Apr 15, 1998</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c449t-e273df9fa6215ec54da4909d4c3e1845bb316db67d79065521be195bc8e69d893</citedby><cites>FETCH-LOGICAL-c449t-e273df9fa6215ec54da4909d4c3e1845bb316db67d79065521be195bc8e69d893</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2244159$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9562049$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LEON-PONTE, M</creatorcontrib><creatorcontrib>ECHEVERRIA DE PEREZ, G</creatorcontrib><creatorcontrib>BIANCO, N</creatorcontrib><creatorcontrib>HENGST, J</creatorcontrib><creatorcontrib>DUBE, S</creatorcontrib><creatorcontrib>LOVE, J</creatorcontrib><creatorcontrib>POIESZ, B. J</creatorcontrib><title>Endemic infection with HTLV-IIB in Venezuelan Indians : Molecular characterization</title><title>Journal of acquired immune deficiency syndromes (1999)</title><addtitle>J Acquir Immune Defic Syndr Hum Retrovirol</addtitle><description>The peripheral blood of 41 Yaruro and Guahibo Indians from Venezuela was examined for HTLV antibodies and DNA. Twenty-five samples (61%) were found to be infected with HTLV-IIB. The sensitivities of the serologic and DNA polymerase chain reaction (PCR) analyses were 80% and 96%, respectively. Epidemiologic studies supported both sexual and perinatal transmission of the virus. Sequence analyses of the HTLV-IIB strains from these Indians indicate that they are unique relative to HTLV-II detected in other groups of humans. HTLV-IIB-G2 isolated from a Guahibo Indian is the most divergent HTLV-IIB strain relative to the prototype HTLV-II NRA.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>AIDS/HIV</subject><subject>Animals</subject><subject>Base Sequence</subject><subject>Biological and medical sciences</subject><subject>Cancer</subject><subject>Cricetinae</subject><subject>Disease Transmission, Infectious</subject><subject>Genetics</subject><subject>HTLV-II Infections - ethnology</subject><subject>HTLV-II Infections - genetics</subject><subject>HTLV-II Infections - transmission</subject><subject>Human T-lymphotropic virus 2 - classification</subject><subject>Human T-lymphotropic virus 2 - genetics</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Indians, South American</subject><subject>Infections</subject><subject>Infectious Disease Transmission, Vertical</subject><subject>Infectious diseases</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Molecular biology</subject><subject>Molecular Sequence Data</subject><subject>Native Americans</subject><subject>Pedigree</subject><subject>Phylogeny</subject><subject>Polymerase Chain Reaction</subject><subject>Prevalence</subject><subject>Sequence Homology, Nucleic Acid</subject><subject>Seroepidemiologic Studies</subject><subject>Venezuela - epidemiology</subject><subject>Viral diseases</subject><subject>Viruses</subject><issn>1077-9450</issn><issn>1525-4135</issn><issn>2331-6993</issn><issn>1944-7884</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkd9rFDEQx4Mo9Vr9E4Qg4ttqsvm145uW2h5cKUjta8gmszRlL1uTXcT-9ebseQ996VNg5jNfMvMhhHL2iTMwnxljslWaNRygY5Ir1tQS5y_IqhWCNxpAvCQrzoxpQCr2mhyXclcJIwQ7IkegdMskrMiPsxRwGz2NaUA_xynR33G-pRfXm5tmvf5W6_QGEz4sOLpE1ylElwr9Qi-nEf0yukz9rcvOz5jjg9sFvCGvBjcWfLt_T8jP72fXpxfN5up8ffp103gpYW6wNSIMMDjdcoVeyeAkMAjSC-SdVH0vuA69NsEA00q1vEcOqvcdaggdiBPy8TH3Pk-_Fiyz3cbicaz_xGkp1kDHBePPg1zXWxq2A98_Ae-mJae6hK1X1UJxIyvUPUI-T6VkHOx9jluX_1jO7E6O_S_HHuTYf3Lq6Lt9_tJvMRwG9zZq_8O-74p345Bd8rEcsLaVNQzEX8CClKU</recordid><startdate>19980415</startdate><enddate>19980415</enddate><creator>LEON-PONTE, M</creator><creator>ECHEVERRIA DE PEREZ, G</creator><creator>BIANCO, N</creator><creator>HENGST, J</creator><creator>DUBE, S</creator><creator>LOVE, J</creator><creator>POIESZ, B. J</creator><general>Raven Press</general><general>Lippincott Williams & Wilkins Ovid Technologies</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T2</scope><scope>7T5</scope><scope>7TK</scope><scope>7U7</scope><scope>7U9</scope><scope>C1K</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>19980415</creationdate><title>Endemic infection with HTLV-IIB in Venezuelan Indians : Molecular characterization</title><author>LEON-PONTE, M ; ECHEVERRIA DE PEREZ, G ; BIANCO, N ; HENGST, J ; DUBE, S ; LOVE, J ; POIESZ, B. J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c449t-e273df9fa6215ec54da4909d4c3e1845bb316db67d79065521be195bc8e69d893</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>AIDS/HIV</topic><topic>Animals</topic><topic>Base Sequence</topic><topic>Biological and medical sciences</topic><topic>Cancer</topic><topic>Cricetinae</topic><topic>Disease Transmission, Infectious</topic><topic>Genetics</topic><topic>HTLV-II Infections - ethnology</topic><topic>HTLV-II Infections - genetics</topic><topic>HTLV-II Infections - transmission</topic><topic>Human T-lymphotropic virus 2 - classification</topic><topic>Human T-lymphotropic virus 2 - genetics</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Indians, South American</topic><topic>Infections</topic><topic>Infectious Disease Transmission, Vertical</topic><topic>Infectious diseases</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Molecular biology</topic><topic>Molecular Sequence Data</topic><topic>Native Americans</topic><topic>Pedigree</topic><topic>Phylogeny</topic><topic>Polymerase Chain Reaction</topic><topic>Prevalence</topic><topic>Sequence Homology, Nucleic Acid</topic><topic>Seroepidemiologic Studies</topic><topic>Venezuela - epidemiology</topic><topic>Viral diseases</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LEON-PONTE, M</creatorcontrib><creatorcontrib>ECHEVERRIA DE PEREZ, G</creatorcontrib><creatorcontrib>BIANCO, N</creatorcontrib><creatorcontrib>HENGST, J</creatorcontrib><creatorcontrib>DUBE, S</creatorcontrib><creatorcontrib>LOVE, J</creatorcontrib><creatorcontrib>POIESZ, B. 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J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Endemic infection with HTLV-IIB in Venezuelan Indians : Molecular characterization</atitle><jtitle>Journal of acquired immune deficiency syndromes (1999)</jtitle><addtitle>J Acquir Immune Defic Syndr Hum Retrovirol</addtitle><date>1998-04-15</date><risdate>1998</risdate><volume>17</volume><issue>5</issue><spage>458</spage><epage>464</epage><pages>458-464</pages><issn>1077-9450</issn><issn>1525-4135</issn><eissn>2331-6993</eissn><eissn>1944-7884</eissn><abstract>The peripheral blood of 41 Yaruro and Guahibo Indians from Venezuela was examined for HTLV antibodies and DNA. Twenty-five samples (61%) were found to be infected with HTLV-IIB. The sensitivities of the serologic and DNA polymerase chain reaction (PCR) analyses were 80% and 96%, respectively. Epidemiologic studies supported both sexual and perinatal transmission of the virus. Sequence analyses of the HTLV-IIB strains from these Indians indicate that they are unique relative to HTLV-II detected in other groups of humans. HTLV-IIB-G2 isolated from a Guahibo Indian is the most divergent HTLV-IIB strain relative to the prototype HTLV-II NRA.</abstract><cop>New York, NY</cop><pub>Raven Press</pub><pmid>9562049</pmid><doi>10.1097/00042560-199804150-00011</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of acquired immune deficiency syndromes (1999), 1998-04, Vol.17 (5), p.458-464 |
| issn | 1077-9450 1525-4135 2331-6993 1944-7884 |
| language | eng |
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| source | MEDLINE; Journals@Ovid LWW Legacy Archive; Free E- Journals; Journals@Ovid Complete |
| subjects | Adolescent Adult Aged Aged, 80 and over AIDS/HIV Animals Base Sequence Biological and medical sciences Cancer Cricetinae Disease Transmission, Infectious Genetics HTLV-II Infections - ethnology HTLV-II Infections - genetics HTLV-II Infections - transmission Human T-lymphotropic virus 2 - classification Human T-lymphotropic virus 2 - genetics Human viral diseases Humans Indians, South American Infections Infectious Disease Transmission, Vertical Infectious diseases Medical sciences Middle Aged Miscellaneous Molecular biology Molecular Sequence Data Native Americans Pedigree Phylogeny Polymerase Chain Reaction Prevalence Sequence Homology, Nucleic Acid Seroepidemiologic Studies Venezuela - epidemiology Viral diseases Viruses |
| title | Endemic infection with HTLV-IIB in Venezuelan Indians : Molecular characterization |
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