Presynaptic inhibition of GABAergic inputs to rat substantia nigra pars reticulata neurones by a cannabinoid agonist

WHOLE-CELL patch-clamp recordings were made from substantia nigra pars reticulata (SNR) neurones in rat midbrain slices to investigate the electrophysiological effects of cannabinoids. The cannabinoid receptor agonist WIN 55212-2 (10 μM) significantly reduced intranigrally evoked and spontaneous inh...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuroreport 1998-03, Vol.9 (4), p.671-675
Hauptverfasser:	Chan, Priscilla K. Y, Chan, Savio C. Y, Yung, Wing-ho
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Benzoxazines Biological and medical sciences Cannabinoids - pharmacology Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Electric Stimulation Evoked Potentials - physiology Fundamental and applied biological sciences. Psychology gamma-Aminobutyric Acid - pharmacology gamma-Aminobutyric Acid - physiology Morpholines - pharmacology Naphthalenes - pharmacology Neurons - drug effects Neurons - physiology Patch-Clamp Techniques Rats Rats, Sprague-Dawley Receptors, Cannabinoid Receptors, Drug - agonists Receptors, Drug - physiology Substantia Nigra - drug effects Substantia Nigra - physiology Synapses - drug effects Synapses - physiology Synaptic Transmission - drug effects Synaptic Transmission - physiology Vertebrates: nervous system and sense organs
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!