Three cases of neonatal herpes simplex virus infection presenting as fulminant hepatitis
We report three cases of neonatal herpes simplex virus (HSV) infection presenting as fulminant hepatitis. None of the patients had clear risk factors for HSV infection and they all died. Antiviral treatment for HSV is currently available but must be administered early in the course of the disease be...
Gespeichert in:
| Veröffentlicht in: | European journal of pediatrics 1990-05, Vol.149 (8), p.555-559 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 559 |
|---|---|
| container_issue | 8 |
| container_start_page | 555 |
| container_title | European journal of pediatrics |
| container_volume | 149 |
| creator | Benador, N Mannhardt, W Schranz, D Braegger, C Fanconi, S Hassam, S Talebzadeh, V Cox, J Suter, S |
| description | We report three cases of neonatal herpes simplex virus (HSV) infection presenting as fulminant hepatitis. None of the patients had clear risk factors for HSV infection and they all died. Antiviral treatment for HSV is currently available but must be administered early in the course of the disease before irreversible liver tissue damage is present. Since the diagnosis may be difficult to establish, we wish to draw the attention of clinicians to the presentation of neonatal HSV infection and suggest that in such cases viral cultures, including culture of liver tissue, should be obtained early and antiviral treatment administered while awaiting the culture results. |
| doi_str_mv | 10.1007/BF01957691 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_79801308</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>79801308</sourcerecordid><originalsourceid>FETCH-LOGICAL-c197t-e89dab017b1610da6b56ef3d86162365447cb1c91127fbc51eb2342bbb2f40713</originalsourceid><addsrcrecordid>eNpFkEFLxDAQRoMo67p68S7k5EGoZpo2aY66uCoseFnBW0nSqRtp05q0ov_eyi56Ghje9zHzCDkHdg2MyZu7FQOVS6HggMwh42kCTIpDMmc8Y4kApY7JSYzvbIIVFDMyS0EAz2BOXjfbgEitjhhpV1OPndeDbugWQz-tomv7Br_opwtjpM7XaAfXedoHjOgH59-ojrQem9Z57Ycp1uvBDS6ekqNaNxHP9nNBXlb3m-Vjsn5-eFrerhMLSg4JFqrShoE000Ws0sLkAmteFQJEykWeZdIasAoglbWxOaBJeZYaY9I6YxL4glzuevvQfYwYh7J10WLT6OmVMZZSFQw4Kybwagfa0MUYsC774Fodvktg5a_G8l_jBF_sW0fTYvWH7r3xHxR4bVM</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>79801308</pqid></control><display><type>article</type><title>Three cases of neonatal herpes simplex virus infection presenting as fulminant hepatitis</title><source>MEDLINE</source><source>SpringerNature Journals</source><creator>Benador, N ; Mannhardt, W ; Schranz, D ; Braegger, C ; Fanconi, S ; Hassam, S ; Talebzadeh, V ; Cox, J ; Suter, S</creator><creatorcontrib>Benador, N ; Mannhardt, W ; Schranz, D ; Braegger, C ; Fanconi, S ; Hassam, S ; Talebzadeh, V ; Cox, J ; Suter, S</creatorcontrib><description>We report three cases of neonatal herpes simplex virus (HSV) infection presenting as fulminant hepatitis. None of the patients had clear risk factors for HSV infection and they all died. Antiviral treatment for HSV is currently available but must be administered early in the course of the disease before irreversible liver tissue damage is present. Since the diagnosis may be difficult to establish, we wish to draw the attention of clinicians to the presentation of neonatal HSV infection and suggest that in such cases viral cultures, including culture of liver tissue, should be obtained early and antiviral treatment administered while awaiting the culture results.</description><identifier>ISSN: 0340-6199</identifier><identifier>EISSN: 1432-1076</identifier><identifier>DOI: 10.1007/BF01957691</identifier><identifier>PMID: 2161341</identifier><language>eng</language><publisher>Germany</publisher><subject>Acute Disease ; Acyclovir - therapeutic use ; Diagnosis, Differential ; Female ; Hepatitis, Viral, Human - diagnosis ; Hepatitis, Viral, Human - drug therapy ; Hepatitis, Viral, Human - etiology ; Hepatitis, Viral, Human - pathology ; Herpes Simplex - complications ; Herpes Simplex - diagnosis ; Herpes Simplex - drug therapy ; Herpes Simplex - pathology ; Humans ; Infant, Newborn ; Male ; Necrosis ; Simplexvirus - isolation & purification ; Time Factors</subject><ispartof>European journal of pediatrics, 1990-05, Vol.149 (8), p.555-559</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c197t-e89dab017b1610da6b56ef3d86162365447cb1c91127fbc51eb2342bbb2f40713</citedby><cites>FETCH-LOGICAL-c197t-e89dab017b1610da6b56ef3d86162365447cb1c91127fbc51eb2342bbb2f40713</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2161341$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Benador, N</creatorcontrib><creatorcontrib>Mannhardt, W</creatorcontrib><creatorcontrib>Schranz, D</creatorcontrib><creatorcontrib>Braegger, C</creatorcontrib><creatorcontrib>Fanconi, S</creatorcontrib><creatorcontrib>Hassam, S</creatorcontrib><creatorcontrib>Talebzadeh, V</creatorcontrib><creatorcontrib>Cox, J</creatorcontrib><creatorcontrib>Suter, S</creatorcontrib><title>Three cases of neonatal herpes simplex virus infection presenting as fulminant hepatitis</title><title>European journal of pediatrics</title><addtitle>Eur J Pediatr</addtitle><description>We report three cases of neonatal herpes simplex virus (HSV) infection presenting as fulminant hepatitis. None of the patients had clear risk factors for HSV infection and they all died. Antiviral treatment for HSV is currently available but must be administered early in the course of the disease before irreversible liver tissue damage is present. Since the diagnosis may be difficult to establish, we wish to draw the attention of clinicians to the presentation of neonatal HSV infection and suggest that in such cases viral cultures, including culture of liver tissue, should be obtained early and antiviral treatment administered while awaiting the culture results.</description><subject>Acute Disease</subject><subject>Acyclovir - therapeutic use</subject><subject>Diagnosis, Differential</subject><subject>Female</subject><subject>Hepatitis, Viral, Human - diagnosis</subject><subject>Hepatitis, Viral, Human - drug therapy</subject><subject>Hepatitis, Viral, Human - etiology</subject><subject>Hepatitis, Viral, Human - pathology</subject><subject>Herpes Simplex - complications</subject><subject>Herpes Simplex - diagnosis</subject><subject>Herpes Simplex - drug therapy</subject><subject>Herpes Simplex - pathology</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Necrosis</subject><subject>Simplexvirus - isolation & purification</subject><subject>Time Factors</subject><issn>0340-6199</issn><issn>1432-1076</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkEFLxDAQRoMo67p68S7k5EGoZpo2aY66uCoseFnBW0nSqRtp05q0ov_eyi56Ghje9zHzCDkHdg2MyZu7FQOVS6HggMwh42kCTIpDMmc8Y4kApY7JSYzvbIIVFDMyS0EAz2BOXjfbgEitjhhpV1OPndeDbugWQz-tomv7Br_opwtjpM7XaAfXedoHjOgH59-ojrQem9Z57Ycp1uvBDS6ekqNaNxHP9nNBXlb3m-Vjsn5-eFrerhMLSg4JFqrShoE000Ws0sLkAmteFQJEykWeZdIasAoglbWxOaBJeZYaY9I6YxL4glzuevvQfYwYh7J10WLT6OmVMZZSFQw4Kybwagfa0MUYsC774Fodvktg5a_G8l_jBF_sW0fTYvWH7r3xHxR4bVM</recordid><startdate>199005</startdate><enddate>199005</enddate><creator>Benador, N</creator><creator>Mannhardt, W</creator><creator>Schranz, D</creator><creator>Braegger, C</creator><creator>Fanconi, S</creator><creator>Hassam, S</creator><creator>Talebzadeh, V</creator><creator>Cox, J</creator><creator>Suter, S</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199005</creationdate><title>Three cases of neonatal herpes simplex virus infection presenting as fulminant hepatitis</title><author>Benador, N ; Mannhardt, W ; Schranz, D ; Braegger, C ; Fanconi, S ; Hassam, S ; Talebzadeh, V ; Cox, J ; Suter, S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c197t-e89dab017b1610da6b56ef3d86162365447cb1c91127fbc51eb2342bbb2f40713</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Acute Disease</topic><topic>Acyclovir - therapeutic use</topic><topic>Diagnosis, Differential</topic><topic>Female</topic><topic>Hepatitis, Viral, Human - diagnosis</topic><topic>Hepatitis, Viral, Human - drug therapy</topic><topic>Hepatitis, Viral, Human - etiology</topic><topic>Hepatitis, Viral, Human - pathology</topic><topic>Herpes Simplex - complications</topic><topic>Herpes Simplex - diagnosis</topic><topic>Herpes Simplex - drug therapy</topic><topic>Herpes Simplex - pathology</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>Necrosis</topic><topic>Simplexvirus - isolation & purification</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Benador, N</creatorcontrib><creatorcontrib>Mannhardt, W</creatorcontrib><creatorcontrib>Schranz, D</creatorcontrib><creatorcontrib>Braegger, C</creatorcontrib><creatorcontrib>Fanconi, S</creatorcontrib><creatorcontrib>Hassam, S</creatorcontrib><creatorcontrib>Talebzadeh, V</creatorcontrib><creatorcontrib>Cox, J</creatorcontrib><creatorcontrib>Suter, S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of pediatrics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Benador, N</au><au>Mannhardt, W</au><au>Schranz, D</au><au>Braegger, C</au><au>Fanconi, S</au><au>Hassam, S</au><au>Talebzadeh, V</au><au>Cox, J</au><au>Suter, S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Three cases of neonatal herpes simplex virus infection presenting as fulminant hepatitis</atitle><jtitle>European journal of pediatrics</jtitle><addtitle>Eur J Pediatr</addtitle><date>1990-05</date><risdate>1990</risdate><volume>149</volume><issue>8</issue><spage>555</spage><epage>559</epage><pages>555-559</pages><issn>0340-6199</issn><eissn>1432-1076</eissn><abstract>We report three cases of neonatal herpes simplex virus (HSV) infection presenting as fulminant hepatitis. None of the patients had clear risk factors for HSV infection and they all died. Antiviral treatment for HSV is currently available but must be administered early in the course of the disease before irreversible liver tissue damage is present. Since the diagnosis may be difficult to establish, we wish to draw the attention of clinicians to the presentation of neonatal HSV infection and suggest that in such cases viral cultures, including culture of liver tissue, should be obtained early and antiviral treatment administered while awaiting the culture results.</abstract><cop>Germany</cop><pmid>2161341</pmid><doi>10.1007/BF01957691</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0340-6199 |
| ispartof | European journal of pediatrics, 1990-05, Vol.149 (8), p.555-559 |
| issn | 0340-6199 1432-1076 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_79801308 |
| source | MEDLINE; SpringerNature Journals |
| subjects | Acute Disease Acyclovir - therapeutic use Diagnosis, Differential Female Hepatitis, Viral, Human - diagnosis Hepatitis, Viral, Human - drug therapy Hepatitis, Viral, Human - etiology Hepatitis, Viral, Human - pathology Herpes Simplex - complications Herpes Simplex - diagnosis Herpes Simplex - drug therapy Herpes Simplex - pathology Humans Infant, Newborn Male Necrosis Simplexvirus - isolation & purification Time Factors |
| title | Three cases of neonatal herpes simplex virus infection presenting as fulminant hepatitis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-26T09%3A14%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Three%20cases%20of%20neonatal%20herpes%20simplex%20virus%20infection%20presenting%20as%20fulminant%20hepatitis&rft.jtitle=European%20journal%20of%20pediatrics&rft.au=Benador,%20N&rft.date=1990-05&rft.volume=149&rft.issue=8&rft.spage=555&rft.epage=559&rft.pages=555-559&rft.issn=0340-6199&rft.eissn=1432-1076&rft_id=info:doi/10.1007/BF01957691&rft_dat=%3Cproquest_cross%3E79801308%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=79801308&rft_id=info:pmid/2161341&rfr_iscdi=true |