Sensitive determination of erythromycin in human plasma by LC-MS/MS

A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the analysis of erythromycin in human plasma (EDTA as anticoagulant) was developed and validated. The concentration ranges were 0.5–50 and 50–5000 ng ml −1. The procedure involved alkalization of 0.5 ml of plasma, one step liquid...

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Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 1998-02, Vol.16 (6), p.961-970
Hauptverfasser:	Li, Yong-Xi, Neufeld, Kathy, Chastain, Jim, Curtis, Alletta, Velagaleti, Poonam
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Anti-Bacterial Agents - blood Average recovery Biological and medical sciences Calibration Chromatography, Liquid Erythromycin - blood General pharmacology Humans Liquid chromatography-tandem mass spectrometry Mass Spectrometry Medical sciences Pharmacology. Drug treatments Quality Control
Online-Zugang:	Volltext
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