Human Placental Lactogenic Hormone as a Parameter for Placental Function in Renal Transplanted Women
In 13 pregnant women with renal transplants the serum concentration of placental hormones were determined in order to show their ability to predict fetal problems especially placental insufficiency. It is shown that the hPL values were increased because of reduced elimination of hPL, presumably in t...
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| Veröffentlicht in: | Acta obstetricia et gynecologica Scandinavica 1990, Vol.69 (1), p.41-43 |
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| container_title | Acta obstetricia et gynecologica Scandinavica |
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| creator | Klebe, Joachim G. Marushak, Andre Bock, Johannes |
| description | In 13 pregnant women with renal transplants the serum concentration of placental hormones were determined in order to show their ability to predict fetal problems especially placental insufficiency. It is shown that the hPL values were increased because of reduced elimination of hPL, presumably in the renal tubuli. In this study the weight of only one newborn was over the 50th percentile in spite of the fact that all but one had hPL values over the 50th percentile and in even 8 pregnancies the values were over the 95th percentile. In most of the growth-retarded fetus's the ratio between hPL and the weight of the newborns was more complex.
It is concluded that in renal transplantated pregnant women, hPL as a parameter for the placental function must be used with reservation and is not able to predict placental insufficiency. |
| doi_str_mv | 10.3109/00016349009021037 |
| format | Article |
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It is concluded that in renal transplantated pregnant women, hPL as a parameter for the placental function must be used with reservation and is not able to predict placental insufficiency.</description><identifier>ISSN: 0001-6349</identifier><identifier>EISSN: 1600-0412</identifier><identifier>DOI: 10.3109/00016349009021037</identifier><identifier>PMID: 2189285</identifier><identifier>CODEN: AOGSAE</identifier><language>eng</language><publisher>Oxford, UK: Informa UK Ltd</publisher><subject>Azathioprine - pharmacology ; Biological and medical sciences ; Body Weight - drug effects ; Creatinine - blood ; Cyclosporins - pharmacology ; Female ; Fetus - anatomy & histology ; Fetus - metabolism ; Gynecology. Andrology. Obstetrics ; Humans ; Kidney Transplantation - physiology ; Management. Prenatal diagnosis ; Medical sciences ; Multicenter Studies as Topic ; Placenta - physiology ; Placental Lactogen - biosynthesis ; Pregnancy ; Pregnancy. Fetus. Placenta</subject><ispartof>Acta obstetricia et gynecologica Scandinavica, 1990, Vol.69 (1), p.41-43</ispartof><rights>1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1990</rights><rights>1990 Acta Obstet Gynecol Scand</rights><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4630-b3836b096f20649aeddbcb1c52b60ebb354e233f9437d0758775d3afb32ebdae3</citedby><cites>FETCH-LOGICAL-c4630-b3836b096f20649aeddbcb1c52b60ebb354e233f9437d0758775d3afb32ebdae3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.3109%2F00016349009021037$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.3109%2F00016349009021037$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,4024,27923,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19344742$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2189285$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Klebe, Joachim G.</creatorcontrib><creatorcontrib>Marushak, Andre</creatorcontrib><creatorcontrib>Bock, Johannes</creatorcontrib><title>Human Placental Lactogenic Hormone as a Parameter for Placental Function in Renal Transplanted Women</title><title>Acta obstetricia et gynecologica Scandinavica</title><addtitle>Acta Obstet Gynecol Scand</addtitle><description>In 13 pregnant women with renal transplants the serum concentration of placental hormones were determined in order to show their ability to predict fetal problems especially placental insufficiency. It is shown that the hPL values were increased because of reduced elimination of hPL, presumably in the renal tubuli. In this study the weight of only one newborn was over the 50th percentile in spite of the fact that all but one had hPL values over the 50th percentile and in even 8 pregnancies the values were over the 95th percentile. In most of the growth-retarded fetus's the ratio between hPL and the weight of the newborns was more complex.
It is concluded that in renal transplantated pregnant women, hPL as a parameter for the placental function must be used with reservation and is not able to predict placental insufficiency.</description><subject>Azathioprine - pharmacology</subject><subject>Biological and medical sciences</subject><subject>Body Weight - drug effects</subject><subject>Creatinine - blood</subject><subject>Cyclosporins - pharmacology</subject><subject>Female</subject><subject>Fetus - anatomy & histology</subject><subject>Fetus - metabolism</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Kidney Transplantation - physiology</subject><subject>Management. Prenatal diagnosis</subject><subject>Medical sciences</subject><subject>Multicenter Studies as Topic</subject><subject>Placenta - physiology</subject><subject>Placental Lactogen - biosynthesis</subject><subject>Pregnancy</subject><subject>Pregnancy. Fetus. Placenta</subject><issn>0001-6349</issn><issn>1600-0412</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU9v1DAQxSMEKkvhA3BA8gVuAf-LHYtTVdFdpBUtsFCJizVxJjQlsRc7Udtvj1e7KkhIcLLs93sz4zdF8ZzR14JR84ZSypSQhlJDOaNCPygWTFFaUsn4w2Kx08sd8Lh4ktJ1vnEt66PiiLPa8LpaFO1qHsGTiwEc-gkGsgY3he_oe0dWIY7BI4FEgFxAhBEnjKQL8Q_-bPZu6oMnvSef0OeXTQSftgP4CVtyGUb0T4tHHQwJnx3O4-LL2bvN6apcny_fn56sSyeVoGUjaqEaalTHqZIGsG0b1zBX8UZRbBpRSeRCdEYK3VJd1VpXrYCuERybFlAcF6_2dbcx_JwxTXbsk8Mhz4JhTlYbbSpa8QyyPehiSCliZ7exHyHeWUbtLln7V7LZ8-JQfG5GbO8dhyiz_vKgQ3IwdDkF16ffhY2QUstdb7XnbvoB7_7f2J6cL5WpaTaWe2OfJry9N0L8YZUWurKXH5b260elPn_T0m4y__bA-7yyEa4QhunKQUR7HeaYV5X-8d1fe5yxFg</recordid><startdate>1990</startdate><enddate>1990</enddate><creator>Klebe, Joachim G.</creator><creator>Marushak, Andre</creator><creator>Bock, Johannes</creator><general>Informa UK Ltd</general><general>Blackwell Publishing Ltd</general><general>Taylor & Francis</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1990</creationdate><title>Human Placental Lactogenic Hormone as a Parameter for Placental Function in Renal Transplanted Women</title><author>Klebe, Joachim G. ; Marushak, Andre ; Bock, Johannes</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4630-b3836b096f20649aeddbcb1c52b60ebb354e233f9437d0758775d3afb32ebdae3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>Azathioprine - pharmacology</topic><topic>Biological and medical sciences</topic><topic>Body Weight - drug effects</topic><topic>Creatinine - blood</topic><topic>Cyclosporins - pharmacology</topic><topic>Female</topic><topic>Fetus - anatomy & histology</topic><topic>Fetus - metabolism</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Kidney Transplantation - physiology</topic><topic>Management. Prenatal diagnosis</topic><topic>Medical sciences</topic><topic>Multicenter Studies as Topic</topic><topic>Placenta - physiology</topic><topic>Placental Lactogen - biosynthesis</topic><topic>Pregnancy</topic><topic>Pregnancy. Fetus. Placenta</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Klebe, Joachim G.</creatorcontrib><creatorcontrib>Marushak, Andre</creatorcontrib><creatorcontrib>Bock, Johannes</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Acta obstetricia et gynecologica Scandinavica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Klebe, Joachim G.</au><au>Marushak, Andre</au><au>Bock, Johannes</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Human Placental Lactogenic Hormone as a Parameter for Placental Function in Renal Transplanted Women</atitle><jtitle>Acta obstetricia et gynecologica Scandinavica</jtitle><addtitle>Acta Obstet Gynecol Scand</addtitle><date>1990</date><risdate>1990</risdate><volume>69</volume><issue>1</issue><spage>41</spage><epage>43</epage><pages>41-43</pages><issn>0001-6349</issn><eissn>1600-0412</eissn><coden>AOGSAE</coden><abstract>In 13 pregnant women with renal transplants the serum concentration of placental hormones were determined in order to show their ability to predict fetal problems especially placental insufficiency. It is shown that the hPL values were increased because of reduced elimination of hPL, presumably in the renal tubuli. In this study the weight of only one newborn was over the 50th percentile in spite of the fact that all but one had hPL values over the 50th percentile and in even 8 pregnancies the values were over the 95th percentile. In most of the growth-retarded fetus's the ratio between hPL and the weight of the newborns was more complex.
It is concluded that in renal transplantated pregnant women, hPL as a parameter for the placental function must be used with reservation and is not able to predict placental insufficiency.</abstract><cop>Oxford, UK</cop><pub>Informa UK Ltd</pub><pmid>2189285</pmid><doi>10.3109/00016349009021037</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0001-6349 |
| ispartof | Acta obstetricia et gynecologica Scandinavica, 1990, Vol.69 (1), p.41-43 |
| issn | 0001-6349 1600-0412 |
| language | eng |
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| source | MEDLINE; Wiley Journals |
| subjects | Azathioprine - pharmacology Biological and medical sciences Body Weight - drug effects Creatinine - blood Cyclosporins - pharmacology Female Fetus - anatomy & histology Fetus - metabolism Gynecology. Andrology. Obstetrics Humans Kidney Transplantation - physiology Management. Prenatal diagnosis Medical sciences Multicenter Studies as Topic Placenta - physiology Placental Lactogen - biosynthesis Pregnancy Pregnancy. Fetus. Placenta |
| title | Human Placental Lactogenic Hormone as a Parameter for Placental Function in Renal Transplanted Women |
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