Extrarenal Wilms' tumor with cerebellar metastasis in a four-year-old girl with spina bifida
This report documents the occurrence of an extrarenal nephroblastoma from which a cerebellar metastasis developed in a four-year-old girl with spina bifida. The second tumor became symptomatic two years after the resection of the primary, suggesting a treatment effect as a factor for the delay in th...
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Veröffentlicht in: | American journal of clinical pathology 1990-06, Vol.93 (6), p.805-809 |
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description | This report documents the occurrence of an extrarenal nephroblastoma from which a cerebellar metastasis developed in a four-year-old girl with spina bifida. The second tumor became symptomatic two years after the resection of the primary, suggesting a treatment effect as a factor for the delay in the growing of the metastatic neoplasm. Histologic and ultrastructural features of the metastasis were similar to those described in Wilms' tumors of the kidney. The pathogenesis of this exceptional association, including malformation, malignancy, and unusual site of metastasis, is discussed. |
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The pathogenesis of this exceptional association, including malformation, malignancy, and unusual site of metastasis, is discussed.</description><subject>Biological and medical sciences</subject><subject>Cerebellar Neoplasms - secondary</subject><subject>Cerebellar Neoplasms - ultrastructure</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Humans</subject><subject>Kidney Neoplasms</subject><subject>Medical sciences</subject><subject>Microscopy, Electron</subject><subject>Neurology</subject><subject>Spina Bifida Occulta - complications</subject><subject>Spinal Cord Neoplasms - complications</subject><subject>Spinal Cord Neoplasms - ultrastructure</subject><subject>Wilms Tumor - complications</subject><subject>Wilms Tumor - secondary</subject><subject>Wilms Tumor - ultrastructure</subject><issn>0002-9173</issn><issn>1943-7722</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtLAzEUhYMotVaXLoUsRFfT5iYzk2QppT6g4EZxIwyZPDQyj5rMoP33TunQrXC5Z3G-e7gchC6BzIFItlBferOQbJ7PBcmO0BRkyhLOKT1GU0IITSRwdorOYvwiBKgg6QRNKOQAAqboffXbBRVsoyr85qs63uKur9uAf3z3ibUNtrRVpQKubafiMD5i32CFXduHZGtVSNrK4A8fqv1J3PhG4dI7b9Q5OnGqivZi1Bl6vV-9LB-T9fPD0_JunWiQGSQZdVRRIaB0zA6Sm9RQx1hGqBbcgEs5MYYxoUjOjRxWLnRGuGZGACcpm6Gbfe4mtN-9jV1R-6h3fze27WPBJZeUpfRfEHIqpMjZACZ7UIc2xmBdsQm-VmFbACl2tRe72otB82KofeCvxuC-rK050GPPg389-ipqVbmgGu3jAUtTygEo-wMR_4mm</recordid><startdate>199006</startdate><enddate>199006</enddate><creator>MIRKIN, L. 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D</au><au>AZZARELLI, B</au><au>IN SOOK SEO</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Extrarenal Wilms' tumor with cerebellar metastasis in a four-year-old girl with spina bifida</atitle><jtitle>American journal of clinical pathology</jtitle><addtitle>Am J Clin Pathol</addtitle><date>1990-06</date><risdate>1990</risdate><volume>93</volume><issue>6</issue><spage>805</spage><epage>809</epage><pages>805-809</pages><issn>0002-9173</issn><eissn>1943-7722</eissn><coden>AJCPAI</coden><abstract>This report documents the occurrence of an extrarenal nephroblastoma from which a cerebellar metastasis developed in a four-year-old girl with spina bifida. The second tumor became symptomatic two years after the resection of the primary, suggesting a treatment effect as a factor for the delay in the growing of the metastatic neoplasm. Histologic and ultrastructural features of the metastasis were similar to those described in Wilms' tumors of the kidney. The pathogenesis of this exceptional association, including malformation, malignancy, and unusual site of metastasis, is discussed.</abstract><cop>Chicago, IL</cop><pub>American Society of Clinical Pathologists</pub><pmid>2161181</pmid><doi>10.1093/ajcp/93.6.805</doi><tpages>5</tpages></addata></record> |
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subjects | Biological and medical sciences Cerebellar Neoplasms - secondary Cerebellar Neoplasms - ultrastructure Child, Preschool Female Humans Kidney Neoplasms Medical sciences Microscopy, Electron Neurology Spina Bifida Occulta - complications Spinal Cord Neoplasms - complications Spinal Cord Neoplasms - ultrastructure Wilms Tumor - complications Wilms Tumor - secondary Wilms Tumor - ultrastructure |
title | Extrarenal Wilms' tumor with cerebellar metastasis in a four-year-old girl with spina bifida |
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