Enzyme inactivation through sulfhydryl oxidation by physiologic NO-carriers

Nitric oxide (NO) is a pluripotent regulatory molecule, yet the molecular mechanisms by which it exerts its effects are largely unknown. Few physiologic target molecules of NO have been identified, and even for these, the modifications caused by NO remain uncharacterized. Human glutathione reductase...

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Veröffentlicht in:Nature Structural Biology 1998-04, Vol.5 (4), p.267-271
Hauptverfasser: Becker, Katja, Savvides, Savvas N, Keese, Michael, Schirmer, R. Heiner, Karplus, P. Andrew
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Sprache:eng
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