Human smooth muscle α-actin gene is a transcriptional target of the p53 tumor suppressor protein

Smooth muscle (sm) alpha-actin is expressed in vascular smooth muscle cells and fibroblast cells. Its expression is regulated by cell proliferation and repressed during oncogenic transformation. In this study, we demonstrate that p53 activation is associated with a dramatic increase in organized mic...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Oncogene 1998-03, Vol.16 (10), p.1299-1308
Hauptverfasser:	COMER, K. A, DENNIS, P. A, ARMSTRONG, L, CATINO, J. J, KASTAN, M. B, CHANDRA KUMAR, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Actins - biosynthesis Actins - genetics Base Sequence Biological and medical sciences Cell proliferation Colorectal Neoplasms Conserved sequence Creatine Creatine kinase Cytoskeleton DNA Primers Fibroblasts - metabolism Fluorescent Antibody Technique, Indirect Fundamental and applied biological sciences. Psychology Humans Kinases Molecular and cellular biology Molecular genetics Molecular Sequence Data Muscle, Smooth, Vascular - metabolism Osteosarcoma p53 Protein Polymerase Chain Reaction Promoter Regions, Genetic Recombinant Proteins - biosynthesis RNA, Messenger - biosynthesis Sequence Deletion Smooth muscle Transcription Transcription, Genetic Transcription. Transcription factor. Splicing. Rna processing Tumor cells Tumor Cells, Cultured Tumor suppressor genes Tumor Suppressor Protein p53 - metabolism Tumor suppressor proteins
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!