Elevated second-trimester amniotic fluid interleukin-6 levels predict preterm delivery

Elevated second-trimester amniotic fluid interleukin-6 levels predict preterm delivery

OBJECTIVE: Our purpose was to determine whether early second-trimester amniotic fluid interleukin-6 levels predict delivery before 34 weeks' gestation. STUDY DESIGN: We used stored second-trimester amniotic fluid samples obtained from women undergoing genetic amniocentesis from 1988 to 1996. In...

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Veröffentlicht in:American journal of obstetrics and gynecology 1998-03, Vol.178 (3), p.546-550
Hauptverfasser: Wenstrom, Katharine D., Andrews, William W., Hauth, John C., Goldenberg, Robert L., DuBard, Mary B., Cliver, Suzanne P.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
amniotic fluid
Amniotic Fluid - metabolism
Biological and medical sciences
Case-Control Studies
Chorioamnionitis - complications
Chorioamnionitis - diagnosis
Female
Gynecology. Andrology. Obstetrics
Humans
Interleukin-6
Interleukin-6 - metabolism
Management. Prenatal diagnosis
Medical sciences
Obstetric Labor, Premature - etiology
Pregnancy
Pregnancy Complications, Infectious - diagnosis
Pregnancy Outcome
Pregnancy Trimester, Second - metabolism
Pregnancy. Fetus. Placenta
preterm delivery
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Zusammenfassung:OBJECTIVE: Our purpose was to determine whether early second-trimester amniotic fluid interleukin-6 levels predict delivery before 34 weeks' gestation. STUDY DESIGN: We used stored second-trimester amniotic fluid samples obtained from women undergoing genetic amniocentesis from 1988 to 1996. Interleukin-6 levels were measured by enzyme-linked immunosorbent assay in samples from every case known to result in delivery from 20 to 34 weeks' gestation ( n = 290), and 290 matched controls delivering at
ISSN:0002-9378
1097-6868
DOI:10.1016/S0002-9378(98)70436-3